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Ubiquitin-fold modifier 1 Antibodies
AND UFM1 ELISA kits, Ubiquitin-fold modifier 1 Proteins
Many biological assays use antibodies to detect Ubiquitin-fold modifier 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ubiquitin-fold modifier 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ubiquitin-fold modifier 1 antibodies...
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UFM1 Overview
Facts about Ubiquitin-fold modifier 1.
Ubiquitin-fold modifier 1 (UFM1)
Ubiquitin-like modifier that may be covalently attached through an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer (PubMed:15071506, PubMed:20018847). The so- called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, as well as the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847).
This post-translational modification on lysine residues of proteins may play a crucial role in several of cellular processes (PubMed:15071506, PubMed:20018847). TRIP4 ufmylation may for example play a role in atomic receptors-mediated transcription (PubMed:25219498).
Gene Information
| Human | |
|---|---|
| Gene Name: | UFM1 |
| Uniprot: | P61960 |
| Entrez: | 51569 |
Family
| Belongs to: |
|---|
| UFM1 family |
Alternative Names
bA131P10.1; BM-002; C13orf20; chromosome 13 open reading frame 20; ubiquitin-fold modifier 1; UFM1
Molecular Weight
Mass (kDA):
9.118 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 13q13.3 |
| Sequence: | 13; NC_000013.11 (38349851..38363619) |
Subcellular Localizations
Nucleus. Cytoplasm.
Diseases
- Diabetes Mellitus
- Physiological Stress
- Endoplasmic Reticulum Stress
- Myocardial Ischemia
- Brain Ischemia
- Ischemia
- Anemia
- Neurodegenerative Disorders
- Occlusion, Middle Cerebral Artery
- Tissue Adhesions
- Arterial Occlusion
- Insulin Resistance
- Dysplasia
Pathways
- Conjugation
- Localization
- Cell Adhesion
- Hibernation
- Cell Division
- Cell Cycle
- Cell Death
- Insulin Secretion
PTMs
- Cleavage
- Sumoylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UFM1
bosterbio.com/bosterbio-gene-info-cards/UFM1
References
PMID: 15071506 by Komatsu M., et al. A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier.
PMID: 16344560 by Kimura K., et al. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.