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- Table of Contents
Facts about Upstream-binding protein 1.
Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity).
Human | |
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Gene Name: | UBP1 |
Uniprot: | Q9NZI7 |
Entrez: | 7342 |
Belongs to: |
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grh/CP2 family |
DKFZp686L1745; LBP1; LBP1A; LBP-1a; LBP1B; LBP-1B; Transcription factor LBP-1; upstream binding protein 1 (LBP-1a); upstream-binding protein 1
Mass (kDA):
60.491 kDA
Human | |
---|---|
Location: | 3p22.3 |
Sequence: | 3; NC_000003.12 (33388336..33440405, complement) |
Expressed in adrenal tissue, JEG-3, NCI-H295A, Hep-G2 and HeLa cell lines.
Nucleus.
PMID: 8114710 by Yoon J.-B., et al. Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro.
PMID: 10644752 by Huang N., et al. Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc.