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UBE2I Antibodies
AND UBE2I ELISA kits, UBE2I Proteins
Many biological assays use antibodies to detect UBE2I, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UBE2I in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UBE2I antibodies...
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UBE2I Infographic by Boster Bio
All UBE2I Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # A02295
100 μg/vial
Cat # A02295
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02295-1
100 μg/vial
Cat # A02295-1
100 μg/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$405
Cat # A02295-2
100ul
Cat # A02295-2
100ul
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02295
100 μl
Cat # M02295
100 μl
UBE2I Overview
Facts about SUMO-conjugating enzyme UBC9.
SUMO-conjugating enzyme UBC9 (UBE2I)
Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the Support of an E3 ligase like RANBP2, CBX4 and ZNF451.
Can catalyze the formation of poly-SUMO chains.Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation.
Gene Information
| Human | |
|---|---|
| Gene Name: | UBE2I |
| Uniprot: | P63279 |
| Entrez: | 7329 |
Family
| Belongs to: |
|---|
| ubiquitin-conjugating enzyme family |
Alternative Names
C358B7.1; EC 6.3.2; EC 6.3.2.-; p18; SUMO-1-protein ligase; SUMO-protein Ligase; Ubc9; UBC9SUMO-conjugating enzyme UBC9; UBCE9; UBE2I; Ubiquitin carrier protein 9; Ubiquitin carrier protein I; ubiquitin conjugating enzyme 9; Ubiquitin-conjugating enzyme E2 I; ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9); ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast); ubiquitin-conjugating enzyme UbcE2A; ubiquitin-like protein SUMO-1 conjugating enzyme; ubiquitin-protein ligase E2I; Ubiquitin-protein ligase I
Molecular Weight
Mass (kDA):
18.007 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16p13.3 |
| Sequence: | 16; NC_000016.10 (1309152..1327017) |
Tissue Specificity
Expressed in heart, skeletal muscle, pancreas, kidney, liver, lung, placenta and brain. Also expressed in testis and thymus.
Subcellular Localizations
Nucleus. Cytoplasm. Mainly nuclear. In spermatocytes, localizes in synaptonemal complexes. Recruited by BCL11A into the nuclear body (By similarity).
Diseases
- Neoplasms
- Cell Transformation, Neoplastic
- Tissue Adhesions
- Microphthalmos
- Waardenburg Syndrome
- Monoclonal Gammapathies
- Monoclonal Gammopathy Of Undetermined Significance
- Carcinogenesis
- Carcinoma
- Neoplasms, Glandular And Epithelial
- Multiple Myeloma
Interacting Proteins
- BHLHE40
- CHMP4B
- DAXX
- DNMT3B
- EDARADD
- ELK1
- GMCL1
- GOLGA2
- HDAC4
- IPO13
Pathways
- Cell Cycle
- Cell Adhesion
- Diplotene
- Mitosis
- Protein Sumoylation
- Oocyte Growth
- Dna Recombination
- M Phase
- Metaphase
- Localization
- Double-strand Break Repair
- Spermatogenesis
- Oocyte Development
PTMs
- Sumoylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UBE2I
bosterbio.com/bosterbio-gene-info-cards/UBE2I
References
PMID: 8668529 by Yasugi T., et al. Identification of the structural and functional human homolog of the yeast ubiquitin conjugating enzyme UBC9.
PMID: 9067428 by Tachibana M., et al. Assignment of the gene for a ubiquitin-conjugating enzyme (UBE2I) to human chromosome band 16p13.3 by in situ hybridization.