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- Table of Contents
Facts about Splicing factor U2AF 65 kDa subunit.
Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly.
Human | |
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Gene Name: | U2AF2 |
Uniprot: | P26368 |
Entrez: | 11338 |
Belongs to: |
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splicing factor SR family |
hU2AF(65); hU2AF65; splicing factor U2AF 65 kD subunit; splicing factor U2AF 65 kDa subunit; U2 (RNU2) small nuclear RNA auxiliary factor 2; U2 auxiliary factor 65 kDa subunit; U2 small nuclear ribonucleoprotein auxiliary factor (65kD); U2 small nuclear RNA auxiliary factor 2; U2AF65U2 snRNP auxiliary factor large subunit
Mass (kDA):
53.501 kDA
Human | |
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Location: | 19q13.42 |
Sequence: | 19; NC_000019.10 (55654132..55674716) |
Nucleus.
PMID: 1538748 by Zamore P.D., et al. Cloning and domain structure of the mammalian splicing factor U2AF.
PMID: 12176931 by Rappsilber J., et al. Large-scale proteomic analysis of the human spliceosome.