Tspyl2 Antibodies

AND Tspyl2 ELISA kits, Tspyl2 Proteins

Many biological assays use antibodies to detect Tspyl2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tspyl2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tspyl2 antibodies...

We validate the specificity of these antibodies to Tspyl2 by testing them on tissues known to express Tspyl2 positively and negatively. Browse below to find the Tspyl2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Tspyl2 Infographic by Boster Bio

All Tspyl2 Products

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Product

Figures

Specificity

Applications

Price

Anti-TSPYL2 Antibody

Human, Mouse, Rat

$405
Cat # A06041
100ul

DENTT (TSPYL2) (NM_022117) Human Over-expression Lysate

Human

$628
Cat # LS064061
100 µg

Tspyl2 Overview

Facts about Testis-specific Y-encoded-like protein 2.

Testis-specific Y-encoded-like protein 2 (Tspyl2)

Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.

Gene Information

Mouse
Gene Name:	Tspyl2
Uniprot:	Q7TQI8
Entrez:	52808

Family

Belongs to:

nucleosome assembly protein (NAP) family

Alternative Names

CASK-interacting nucleosome assembly protein; CDA1CTCL-associated antigen se20-4; Cell division autoantigen 1; CINAPSE20-4; CTCL tumor antigen se20-4; CTCL; Cutaneous T-cell lymphoma-associated antigen se20-4; cutaneous T-cell lymphoma-associated tumor antigen se20-4; DENTTTSPY-like protein 2; differentially expressed nucleolar TGF-beta1 target; Differentially-expressed nucleolar TGF-beta1 target protein; HRIHFB2216; NP79; Nuclear protein of 79 kDa; SE204; testis-specific protein Y encoded-like 2; testis-specific Y-encoded-like protein 2; TSPX; TSPY-like 2

Molecular Weight

Mass (kDA):
77.671 kDA

Genomic Context


Mouse

Location:	X F3\|X 68.46 cM
Sequence:	X;

Tissue Specificity

Present at high levels in the pituitary gland and at moderate levels in adrenal gland, brain, testis and ovary. In brain, expressed both in mature neurons and progenitor cells (at protein level).

Diseases

Neoplasms
Diabetic Angiopathies
Cardiovascular Diseases
Malignant Neoplasms
Diabetes Mellitus, Experimental
Von Hippel-lindau Syndrome
Endometrial Carcinoma
Endometrial Polyp
Pathological Process

Atherosclerosis
Embryonic Mosaic
Diabetes Mellitus

Pathways

Cell Cycle
Methylation
Cell Division
Nucleosome Assembly
Cell Proliferation
Dna Repair
Pathogenesis

Chromosome Segregation
Chromatin Remodeling

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Tspyl2

References

PMID: 12619135 by Ozbun L.L., et al. Differentially expressed nucleolar TGF-beta1 target (DENTT) in mouse development.

PMID: 15066269 by Wang G.-S., et al. Transcriptional modification by a CASK-interacting nucleosome assembly protein.