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TNFRSF18 Antibodies
AND TNFRSF18 ELISA kits, TNFRSF18 Proteins
Many biological assays use antibodies to detect TNFRSF18, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNFRSF18 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNFRSF18 antibodies...
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TNFRSF18 Infographic by Boster Bio
All TNFRSF18 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK0768
96 wells/kit, with removable strips.
Cat # EK0768
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK0769
96 wells/kit, with removable strips.
Cat # EK0769
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK0768
96 wells/kit, with removable strips.
Cat # FEK0768
96 wells/kit, with removable strips.
Human
Flow Cytometry, WB
$523
Cat # M03125-1
100 µl
Cat # M03125-1
100 µl
Human
Flow Cytometry, WB
$523
Cat # M03125
100 µl
Cat # M03125
100 µl
TNFRSF18 Overview
Facts about Tumor necrosis factor receptor superfamily member 18.
Tumor necrosis factor receptor superfamily member 18 (TNFRSF18)
Receptor for TNFSF18.
Appears to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death.Mediated NF-kappa-B activation through the TRAF2/NIK pathway. .
Gene Information
| Human | |
|---|---|
| Gene Name: | TNFRSF18 |
| Uniprot: | Q9Y5U5 |
| Entrez: | 8784 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Activation-inducible TNFR family receptor; AITR; AITRTNF receptor superfamily activation-inducible protein; CD357 antigen; CD357; GITR; GITR-D; GITRtumor necrosis factor receptor superfamily member 18; Glucocorticoid-induced TNFR-related protein; TNFRSF18; tumor necrosis factor receptor superfamily, member 18
Molecular Weight
Mass (kDA):
26 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p36.33 |
| Sequence: | 1; NC_000001.11 (1203508..1207901, complement) |
Tissue Specificity
Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.
Subcellular Localizations
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
Diseases
- Inflammation
- Neoplasms
- Autoimmune Reaction
- Malignant Neoplasms
- Autoimmune Diseases
- Autoimmunity
- Decreased Immunologic Activity [pe]
- Infective Disorder
- Hiv Infections
- Carcinoma
- Melanoma
- Arthritis
Interacting Proteins
- TNFSF18
Pathways
- Immune Response
- Cytokine Production
- Secretion
- Cell Activation
- T Cell Activation
- Cell Proliferation
- Pathogenesis
- T Cell Proliferation
- Cell Death
- Inflammatory Response
- Cytokine Secretion
- Cell Cycle
- Hypersensitivity
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNFRSF18
bosterbio.com/bosterbio-gene-info-cards/TNFRSF18
References
PMID: 10074428 by Gurney A.L., et al. Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR.
PMID: 10037686 by Kwon B., et al. Identification of a novel activation-inducible protein of the tumor necrosis factor receptor superfamily and its ligand.