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- Table of Contents
3 Citations 6 Q&As
Facts about Thrombopoietin.
It might be the major physiological regulator of circulating platelets. .
Human | |
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Gene Name: | THPO |
Uniprot: | P40225 |
Entrez: | 7066 |
Belongs to: |
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EPO/TPO family |
Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; megakaryocyte stimulating factor; MGDF; MGDFC-mpl ligand; MKCSF; MK-CSF; ML; MPL ligand; MPLLG; MPLLGMGC163194; Myeloproliferative leukemia virus oncogene ligand; THCYT1; THPO; thrombopoietin nirs variant 1; Thrombopoietin; Tpo; TPOMKCSF
Mass (kDA):
37.823 kDA
Human | |
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Location: | 3q27.1 |
Sequence: | 3; NC_000003.12 (184371935..184379688, complement) |
Secreted.
PMID: 8202154 by de Sauvage F.J., et al. Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand.
PMID: 8020099 by Bartley T.D., et al. Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl.
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