Tyrosine 3-monooxygenase Antibodies

Tyrosine 3-monooxygenase (TH)

Plays an essential role in the physiology of adrenergic neurons. .

Gene Information

Human
Gene Name:	TH
Uniprot:	P07101
Entrez:	7054

Family

Belongs to:
biopterin-dependent aromatic amino acid hydroxylase family

Alternative Names

TH; DYT14; DYT5b; EC 1.14.16; EC 1.14.16.2; TH mouse; TH; TYH dystonia 14; TYH; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; Tyrosine Hydroxylase immunohistochemistry; Tyrosine Hydroxylase mouse; Tyrosine Hydroxylase

Molecular Weight

Mass (kDA):
58.6 kDA

Genomic Context

Human
Location:	11p15.5
Sequence:	11; NC_000011.10 (2163929..2174081, complement)

Tissue Specificity

Mainly expressed in the brain and adrenal glands.

Diseases

• Parkinson Disease
• Nervousness
• Disease Of Adrenal Medulla
• Secondary Parkinson Disease
• Nerve Degeneration
• Neoplasms
• Pituitary Diseases
• Hypothyroidism
• Neurotoxicity Syndromes
• Neuroblastoma
• Neurodegenerative Disorders
• Malignant Neoplasms
• Hypoxia

• Depressive Disorder
• Inflammation
• Pheochromocytoma
• Varicosity
• Mptp Poisoning
• Pain
• Hypertensive Disease

Pathways

• Innervation
• Localization
• Secretion
• Pathogenesis
• Cell Death
• Transport
• Aging
• Brain Development
• Neuroprotection
• Immune Response
• Cell Proliferation
• Regeneration
• Neurogenesis

• Hypersensitivity
• Cell Differentiation
• Sensitization
• Translation
• Lactation
• Dopamine Uptake
• Reflex

PTMs

• Phosphorylation
• Reduction
• Oxidation
• Cleavage
• Hydroxylation
• Carboxylation
• Deiodination
• Methylation
• Dephosphorylation
• Nitration

• Acetylation
• Biotinylation
• Glycosylation
• Decarboxylation
• Demethylation
• Bromination
• Ubiquitination
• Iodination
• Deacetylation
• Deamination

Research Areas

• Cancer
• Lipid and Metabolism
• Neurodegeneration
• Neuronal Cell Markers
• Neuroscience

• Neurotransmission
• Phospho-Specific
• Prostate Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TH

Best Uses Of The TH Marker

There are a myriad of applications for TH markers However, how do you know which one is best for you? This article will provide information on the different types of Boster Bio anti-TH markers. It will also discuss Boster Bio's CD86 (Dendritic Cells Maturation Marker) antibody and its Picoband format. Learn why TH markers are essential in your research and how you can choose the most appropriate one for your needs.

Boster Bio Anti-GAPDH

The Boster Bio Anti-GAPDH is a primary antibody that reacts with human GAPDH. It is also available as a Picoband that can be kept at -20C for one year and then frozen for 6 months. The antibody contains 5 mg of BSA. Depending on your immunogen length it is possible that you will require an inhibitory peptide. You can purchase a variety of antibodies if you don't require an inhibitory protein.

Boster Bio Anti-CD86

The Boster Bio Anti-CD86 Monoclonal Antibody reacts to both Mouse and Human cells. The antibody can be stored frozen at -20C up to six months or for a year. It contains 5 mg BSA and 0.05 mg Thimerosal. It is also available as blocking peptides for a specific length of the immunogen. You can purchase the blocking peptides with different sizes and concentrations.

Scientists may submit results for specific species, species, applications and can be eligible for product credits. The product is used all over the world by scientists. All scientists are eligible apply. Its most effective use is in cancer research. Researchers using immunotherapy for cancer may publish their findings in an academic journal. Boster scientists can earn product credits for their work.

Boster Bio Anti-GAPDH Picoband

This boster bio antibody reacts to Human, Mouse, Rat and Chicken GAPDH. The Boster Bio Anti-GAPDH antibody Picoband is sold in PBS which contains 0.09 percent sodium azide. The antibody is produced by Saturated Ammonium Sulfate precipitation and dialysis in PBS. The boster bio-antibody is produced by rabbits that have been immunized with KLH conjugated peptide.

The Boster Bio Anti-GAPDH picokine (tm) is an extremely sensitive ELISA kit that has been validated for use in a wide range of samples. The validation procedure is included in the kit. Images of the validation procedure can be requested. Supervision(tm) is boster bio's feature that reduces time and improves background. Boster Bio Anti-GAPDH Picoband comes with exceptional technical support and a no-cost trial.

Visit the official website to verify the Boster Bio Anti GPDH Pic-Band. Boster Bio tests each product using known positive and negative samples to guarantee safety. The Boster Bio Anti-GAPDH Picoband can be purchased at any online shop or biopharmacy distributor. While it is not necessary to purchase the Boster Bio Anti GPDH Pic-Band we recommend purchasing this antibody if planning to use it for bioanalytic use.

The manufacturer of Boster Bio Anti-GAPDH Pic-Band claims that the product is safe for human use and is made up of a biochemical known as Mei Zhong Chan Jun. It is also known by its Chinese name, Bo Si Te Sheng Wu Ji Shu. It is not recommended to use on animals. Boster Bio Anti–GAPDH pic-band should not be used if you have an illness or family history of GAPDH gene mutations.

Boster Bio Anti-CD86 (Dendritic Cells Maturation Marker)

GM-CSF is an important inducer of dendritic cell maturation. Silestrol could be a potential inhibitor. Silvestrol is capable of reducing certain MdDC surface markers, such as CD86 and CD206. However the effects of silvestrol weren't observed on other MdDC surface markers, such as CD54, CD206, and HLA-DR.

In this test, GM-DCs and BM neutrophils were stimulated by 10 mM of IL-12p35 and 10 mg of poly(I:C). The samples were then tested for the presence of CD86 and IL-12p35. Boster Bio Anti-CD86 (Dendritic Cells Maturation Marker), was utilized in addition to the primary reagents. It was also tested against a variety of cytokines including human GM-CSF and human TNF-a.

To conduct the test, 1.5-2 x 105 cells from each sample were treated with human FcR Blocking Reagent for 15 minutes at a temperature of 4 degrees Celsius. After blocking, the samples were stained with up to 7 uL of surface marker antibody. The samples were then stained with 250 uL of 10% FCS/PBS. The samples were analysed using an MACSQuant(r) Analyzer 10 flow cytometer. After the samples had been stained, they were resuspended in 100 uL of PBS. After staining the samples, they were tested using a Boster Bio MACSQuant(r) Analyzer v10. FlowJo software v10. was used to calculate the geometric mean intensity of fluorescent.

Human CD86 antibodies can be used for the analysis of CD86 expression in flow cytometry or IP applications. These antibodies react with monoclonal antibodies against CD86 monoclonal antibodies of mice and humans. The blocking peptide is available at 1.0mg/l or 1 mg/mg/WB. After determining the antigen-antibody-antigen-antibody complex, the antibody can be used to analyze the cell surface and determine cellular function.