TGM5 Antibodies

AND TGM5 ELISA kits, TGM5 Proteins

Many biological assays use antibodies to detect TGM5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TGM5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TGM5 antibodies...

We validate the specificity of these antibodies to TGM5 by testing them on tissues known to express TGM5 positively and negatively. Browse below to find the TGM5 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TGM5 Infographic by Boster Bio

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Anti-TGM5 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A08563
0.1 mg

TGM5 Overview

Facts about Protein-glutamine gamma-glutamyltransferase 5.

TGM5 3D structure. Source: alphafold

Protein-glutamine gamma-glutamyltransferase 5 (TGM5)

Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes.

Gene Information

Human
Gene Name:	TGM5
Uniprot:	O43548
Entrez:	9333

Family

Belongs to:

transglutaminase superfamily

Alternative Names

EC 2.3.2.13; protein-glutamine gamma-glutamyltransferase 5; TG(X); TGase X; TGASE5; TGase-5; TGASEX; TGM6; TGMX; TGXMGC141907; transglutaminase 5; transglutaminase V; Transglutaminase X; transglutaminase-5

Molecular Weight

Mass (kDA):
80.778 kDA

Genomic Context


Human

Location:	15q15.2
Sequence:	15; NC_000015.10 (43232590..43266928, complement)

Tissue Specificity

Expressed in foreskin keratinocytes.

Subcellular Localizations

Cytoplasm. Associated with intermediate filaments.

Diseases

Peeling Skin Syndrome, Acral Type
Dermatologic Disorders
Bulla
Epidermolysis Bullosa
Dermatitis, Atopic
Exfoliative Dermatitis
Dermatitis
Psoriasis
Pigmentation Disorders
Skin Diseases, Genetic
Head And Neck Carcinoma

Allergy-sensitivity To Fungi Syndrome
Carcinoma
Sicca Syndrome
Vesicular Eczema Of Hands And/or Feet
Dermatitis, Irritant

Pathways

Cornification
Cell Differentiation
Epithelial Cell Differentiation
Pathogenesis
Cell-cell Adhesion

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TGM5

References

PMID: 9452468 by Aeschlimann D., et al. Isolation of a cDNA encoding a novel member of the transglutaminase gene family from human keratinocytes. Detection and identification of transglutaminase gene products based on reverse transcription- polymerase chain reaction with degenerate primers.

PMID: 11390390 by Grenard P., et al. Evolution of transglutaminase genes: identification of a transglutaminase gene cluster on human chromosome 15q15. Structure of the gene encoding transglutaminase X and a novel gene family member, transglutaminase Z.