DNA-directed RNA polymerase I subunit RPA43 (Twistnb)

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.

Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters. .