This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about E3 ubiquitin-protein ligase TRIM33.
May behave as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade.
Human | |
---|---|
Gene Name: | TRIM33 |
Uniprot: | Q9UPN9 |
Entrez: | 51592 |
Belongs to: |
---|
TRIM/RBCC family |
E3 ubiquitin-protein ligase TRIM33; EC 6.3.2; EC 6.3.2.-; Ectodermin homolog; KIAA1113; Protein Rfg7; PTC7FLJ32925; RET-fused gene 7 protein; RFG7FLJ11429; TF1G; TIF1GAMMA; TIF1-gamma; TIF1GECTO; TIFGAMMA; Transcription intermediary factor 1-gamma; transcriptional intermediary factor 1 gamma; tripartite motif containing 33; tripartite motif-containing 33; Tripartite motif-containing protein 33
Mass (kDA):
122.533 kDA
Human | |
---|---|
Location: | 1p13.2 |
Sequence: | 1; NC_000001.11 (114392787..114511203, complement) |
Expressed in stem cells at the bottom of the crypts of the colon (at protein level). Expressed in colon adenomas and adenocarcinomas (at protein level). Expressed in brain, lung, liver, spleen, thymus, prostate, kidney, testis, heart, placenta, pancreas, small intestine, ovary, colon, skeletal muscle and hematopoietic progenitors.
Nucleus. In discrete nuclear dots resembling nuclear bodies.
PMID: 10022127 by Venturini L., et al. TIF1gamma, a novel member of the transcriptional intermediary factor 1 family.
PMID: 11331580 by Reymond A., et al. The tripartite motif family identifies cell compartments.