TRAK1 Antibodies

AND TRAK1 ELISA kits, TRAK1 Proteins

Many biological assays use antibodies to detect TRAK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRAK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRAK1 antibodies...

We validate the specificity of these antibodies to TRAK1 by testing them on tissues known to express TRAK1 positively and negatively. Browse below to find the TRAK1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRAK1 Infographic by Boster Bio

All TRAK1 Products

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Product

Figures

Specificity

Applications

Price

Anti-TRAK1 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A06551
100ul

TRAK1 (NM_014965) Human Recombinant Protein

$1249
Cat # PROTQ9UPV9
20 µg

TRAK1 (NM_014965) Human Over-expression Lysate

Human

$628
Cat # LS022906
100 µg

TRAK1 Overview

Facts about Trafficking kinesin-binding protein 1.

TRAK1 3D structure. Source: alphafold

Trafficking kinesin-binding protein 1 (TRAK1)

Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors (PubMed:18675823). Involved in mitochondrial motility.

When O-glycosylated, abolishes mitochondrial motility. Crucial for recruiting OGT to the mitochondrial surface of neuronal processes (PubMed:24995978).

Gene Information

Human
Gene Name:	TRAK1
Uniprot:	Q9UPV9
Entrez:	22906

Family

Belongs to:

milton family

Alternative Names

106 kDa O-GlcNAc transferase-interacting protein; KIAA1042OGT(O-Glc-NAc transferase)-interacting protein 106 KDa; OIP106OGT(O Glc NAc transferase) interacting protein 106 KDa; trafficking kinesin-binding protein 1; trafficking protein, kinesin binding 1

Molecular Weight

Mass (kDA):
106.04 kDA

Genomic Context


Human

Location:	3p22.1
Sequence:	3; NC_000003.12 (42013802..42225890)

Tissue Specificity

High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.

Subcellular Localizations

Cytoplasm. Nucleus. Mitochondrion. Early endosome. Endosome. Mitochondrion membrane. Cytoplasm, cell cortex. Predominantly associated with early endosome. The localization to early endosomes depends on its interaction with HGS/HRS (PubMed:18675823). Colocalizes with MGARP at the mitochondria (PubMed:19528298).

Diseases

Malignant Neoplasms
Spinal Cord Injuries
Carcinoma
Parkinson Disease
Neoplasms
Cerebrovascular Accident
Colorectal Cancer
Cerebral Palsy
Dystonia Disorders
Malignant Neoplasm Of Stomach
Colorectal Neoplasms
Muscle Hypertonia

Stomach Neoplasms
Adenoma
Neoplasm Metastasis
Idiopathic Generalized Epilepsy
Epilepsy, Generalized
Malignant Neoplasm Of Brain
Carcinogenesis

Interacting Proteins

Kif5b
OGT
Ogt
RHOT1
RHOT2

Pathways

Transport
Gene Silencing
Localization

PTMs

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRAK1

References

PMID: 24995978 by Pekkurnaz G., et al. Glucose regulates mitochondrial motility via Milton modification by O-GlcNAc transferase.

PMID: 12435728 by Iyer S.P.N., et al. Identification and cloning of a novel family of coiled-coil domain proteins that interact with O-GlcNAc transferase.