TRAF5 Antibodies

AND TRAF5 ELISA kits, TRAF5 Proteins

Many biological assays use antibodies to detect TRAF5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRAF5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRAF5 antibodies...

We validate the specificity of these antibodies to TRAF5 by testing them on tissues known to express TRAF5 positively and negatively. Browse below to find the TRAF5 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRAF5 Infographic by Boster Bio

All TRAF5 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-TRAF5 Antibody Picoband®

7 Q&As

Human

$370
Cat # PA2154
100 μg/vial

Anti-TRAF-5 Antibody

Human, Mouse, Rat

IP, IHC, WB

$328
Cat # A03076
50 µl

Anti-TRAF5 Antibody Picoband®

Human, Mouse, Rat

$370
Cat # A03076-1
100 μg/vial

TRAF5 (NM_004619) Human Recombinant Protein

$1249
Cat # PROTO00463
20 µg

Anti-TRAF5 Mouse Monoclonal Antibody [Clone ID: OTI7A3]

Human

$523
Cat # M03076
100 µl

TRAF5 (NM_004619) Human Over-expression Lysate

Human

$960
Cat # LS007188
100 µg

TRAF5 Overview

Facts about TNF receptor-associated factor 5.

TRAF5 3D structure. Source: alphafold

TNF receptor-associated factor 5 (TRAF5)

Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and likely JNK.

Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.

Gene Information

Human
Gene Name:	TRAF5
Uniprot:	O00463
Entrez:	7188

Family

Belongs to:

TNF receptor-associated factor family

Alternative Names

MGC:39780; RNF84; RNF84RING finger protein 84; TNF receptor-associated factor 5; TRAF5; TRAF-5

Molecular Weight

Mass (kDA):
64.406 kDA

Genomic Context


Human

Location:	1q32.3
Sequence:	1; NC_000001.11 (211326594..211374946)

Tissue Specificity

Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood.

Subcellular Localizations

Cytoplasm. Cytoplasm, cytosol.

Diseases

Neoplasms
Lymphoma
Inflammation
Malignant Neoplasms
Tissue Adhesions
B-cell Lymphomas
Leukemia
Autoimmunity
Hodgkin Disease
Autoimmune Reaction
Immunologic Deficiency Syndromes
Lymphoma, Non-hodgkin
Leukemogenesis

Carcinoma
Trance State
Virus Diseases
Intestinal Diseases
Tumor Angiogenesis
Malignant Paraganglionic Neoplasm
Diffuse Large B-cell Lymphoma

Interacting Proteins

CCDC184
FBXO28
GORASP2
HOMER1
HSF2BP

NMI
RAD23A
SDCBP
SEC13
SERPINB9

SRSF1
THAP1
TNFRSF14
TRAF3
TRAF6

ZFAND6

Pathways

Cell Death
Immune Response
Cell Activation
Cell Proliferation
Pathogenesis
Osteoclast Differentiation
Localization
Cell Growth
Secretion
T Cell Activation
Cell Differentiation
Cytokine Production
Angiogenesis

Rna Interference
Cell Migration
Chemokine Production
Neutrophil Extravasation
Mammary Gland Development
B Cell Activation
Type I Interferon Production

PTMs

Phosphorylation
Ubiquitination

Cleavage
Dephosphorylation

Myristoylation

Research Areas

Apoptosis
Signal Transduction
Zinc Finger

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRAF5

References

PMID: 9511754 by Mizushima S., et al. Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5).

PMID: 9177772 by Nakano H., et al. Human TNF receptor-associated factor 5 (TRAF5): cDNA cloning, expression and assignment of the TRAF5 gene to chromosome 1q32.