TRAF3 Antibodies

AND TRAF3 ELISA kits, TRAF3 Proteins

Many biological assays use antibodies to detect TRAF3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRAF3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRAF3 antibodies...

We validate the specificity of these antibodies to TRAF3 by testing them on tissues known to express TRAF3 positively and negatively. Browse below to find the TRAF3 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRAF3 Infographic by Boster Bio

All TRAF3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-TRAF3 Antibody Picoband®

7 Q&As

Human, Mouse, Rat

$370
Cat # PA2008
100 μg/vial

Anti-TRAF3 Antibody Picoband®

Human, Mouse, Rat

ELISA, WB

$370
Cat # A00424
100 μg/vial

Anti-TRAF3 Antibody

Human, Mouse, Rat

ELISA, ICC, WB

$449
Cat # A00424-1
0.1 mg

Anti-TRAF3 (S289) Antibody

Human

$405
Cat # A00424S289
100ul

Anti-TRAF3 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$405
Cat # A00424-2
100ul

TRAF3 (NM_145725) Human Over-expression Lysate

Human

$628
Cat # LS007187
100 µg

TRAF3 Overview

Facts about TNF receptor-associated factor 3.

TNF receptor-associated factor 3 (TRAF3)

Regulates pathways leading to the activation of NF- kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon.

Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses.

Gene Information

Human
Gene Name:	TRAF3
Uniprot:	Q13114
Entrez:	7187

Family

Belongs to:

TNF receptor-associated factor family

Alternative Names

CAP1; CAP-1CD40 receptor associated factor 1; CD40 associated protein 1; CD40 binding protein; CD40 receptor-associated factor 1; CD40-binding protein; CD40bp; CRAF1; CRAF1CAP1; LAP1; LAP1CD40BP; LMP1-associated protein 1; TNF receptor-associated factor 3; TRAF3; TRAF-3

Molecular Weight

Mass (kDA):
64.49 kDA

Genomic Context


Human

Location:	14q32.32
Sequence:	14; NC_000014.9 (102777449..102911500)

Subcellular Localizations

Cytoplasm. Endosome. Mitochondrion. Undergoes endocytosis together with TLR4 upon LPS signaling (By similarity). Associated with mitochondria in response to virus.

Diseases

Neoplasms
Malignant Neoplasms
Lymphoma
Virus Diseases
Carcinoma
Inflammation
B-cell Lymphomas
Multiple Myeloma
Innate Immune Response
Infective Disorder
Hodgkin Disease
Autoimmunity

Autoimmune Reaction
Autoimmune Diseases
Malignant Paraganglionic Neoplasm
Tissue Adhesions
Stomatitis
Vesicular Stomatitis
Hypergammaglobulinemia

Interacting Proteins

Azi2
BRAF
CD40
EDA2R
IP6K3

Irf1
LTBR
MAP3K14
PTPN22
RIPK2

SNAP29
TANK
TRAF3IP1
TRAF5
WDR5

ZMYND11

Pathways

Cell Death
Immune Response
Localization
Pathogenesis
Cell Activation
Cytokine Production
Secretion
B Cell Activation
Cell Proliferation
Type I Interferon Production
Isotype Switching
Innate Immune Response
Cell Growth

Cell Cycle
Cell Differentiation
B Cell Differentiation
T Cell Activation
B Cell Proliferation
Cytokine Secretion
Virulence

PTMs

Phosphorylation
Ubiquitination
Cleavage
Glutathionylation

Reduction
Glycosylation
Acetylation
Myristoylation

Research Areas

Apoptosis
Immunology
Innate Immunity
Zinc Finger

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRAF3

References

PMID: 7527023 by Hu H.M., et al. A novel RING finger protein interacts with the cytoplasmic domain of CD40.

PMID: 7859281 by Mosialos G., et al. The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family.