TPST2 Antibodies

AND TPST2 ELISA kits, TPST2 Proteins

Many biological assays use antibodies to detect TPST2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TPST2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TPST2 antibodies...

We validate the specificity of these antibodies to TPST2 by testing them on tissues known to express TPST2 positively and negatively. Browse below to find the TPST2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TPST2 Infographic by Boster Bio

All TPST2 Products

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Product

Figures

Specificity

Applications

Price

TPST2 (NM_001008566) Human Recombinant Protein

$813
Cat # PROTO60704
20 µg

TPST2 (NM_001008566) Human Over-expression Lysate

Human

$628
Cat # LS008459
100 µg

TPST2 Overview

Facts about Protein-tyrosine sulfotransferase 2.

TPST2 3D structure. Source: alphafold

Protein-tyrosine sulfotransferase 2 (TPST2)

Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate. .

Gene Information

Human
Gene Name:	TPST2
Uniprot:	O60704
Entrez:	8459

Family

Belongs to:

protein sulfotransferase family

Alternative Names

EC 2.8.2.20; TPST2; TPST-2; tyrosylprotein phosphotransferase 2; Tyrosylprotein Sulfotransferase 2; tyrosylprotein sulfotransferase 2protein-tyrosine sulfotransferase 2; tyrosylprotein sulfotransferase-2

Molecular Weight

Mass (kDA):
41.912 kDA

Genomic Context


Human

Location:	22q12.1
Sequence:	22; NC_000022.11 (26521996..26590132, complement)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Infertility
Hypothyroidism
Congenital Hypothyroidism
Tissue Adhesions
Dwarfism
Hypoplasia Of Thyroid
Male Infertility
Growth Retardation
Hypoplasia
Cell Invasion
Atherosclerosis
Growth Disorders

Cholangiocarcinoma
Pancreatitis
Asthma
Hyperlipidemia
Hyperglycemia
Primary Hypothyroidism

Pathways

Sulfation
Transport
Cell Adhesion
Secretory Pathway
Parturition
Insulin Secretion
Fertilization
Dna Repair
Membrane Fusion
Virulence
Copulation
Localization
Spermatogenesis

Translation
Sperm Motility
Mating
Exocytosis
Pathogenesis
Secretion
Parasitism

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TPST2

References

PMID: 9736702 by Beisswanger R., et al. Existence of distinct tyrosylprotein sulfotransferase genes: molecular characterization of tyrosylprotein sulfotransferase-2.

PMID: 9733778 by Ouyang Y.-B., et al. Molecular cloning and expression of human and mouse tyrosylprotein sulfotransferase-2 and a tyrosylprotein sulfotransferase homologue in Caenorhabditis elegans.