TP53BP2 Antibodies

AND TP53BP2 ELISA kits, TP53BP2 Proteins

Many biological assays use antibodies to detect TP53BP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TP53BP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TP53BP2 antibodies...

We validate the specificity of these antibodies to TP53BP2 by testing them on tissues known to express TP53BP2 positively and negatively. Browse below to find the TP53BP2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TP53BP2 Infographic by Boster Bio

All TP53BP2 Products

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Product

Figures

Specificity

Applications

Price

Anti-ASPP2 TP53BP2 Antibody

3 Q&As

Human

ELISA, WB

$629
Cat # A02609
100ug

Anti-ASPP2 Rabbit Monoclonal Antibody

2 Q&As

Human

IF, IHC, ICC, WB

$370
Cat # M02609
100 μl

Anti-TP53BP2 Antibody

Human, Mouse

$405
Cat # A02609-1
100ul

Anti-ASPP2 TP53BP2 Antibody

Human

IF, IHC, ICC, WB

$405
Cat # A02609-2
100ul

TP53BP2 (NM_001031685) Human Over-expression Lysate

Human

$628
Cat # LS007159
100 µg

TP53BP2 Overview

Facts about Apoptosis-stimulating of p53 protein 2.

TP53BP2 3D structure. Source: alphafold

Apoptosis-stimulating of p53 protein 2 (TP53BP2)

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.

Inhibits the capacity of APPBP1 into conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M.

Gene Information

Human
Gene Name:	TP53BP2
Uniprot:	Q13625
Entrez:	7159

Family

Belongs to:

ASPP family

Alternative Names

apoptosis-stimulating protein of p53, 2; ASPP2P53BP2,53BP2apoptosis-stimulating of p53 protein 2; Bbp; Bcl2-binding protein; p53-binding protein 2; p53BP2; PPP1R13A; Renal carcinoma antigen NY-REN-51; tumor protein p53 binding protein, 2; tumor protein p53-binding protein, 2; Tumor suppressor p53-binding protein 2

Molecular Weight

Mass (kDA):
125.616 kDA

Genomic Context


Human

Location:	1q41
Sequence:	1; NC_000001.11 (223779893..223845972, complement)

Tissue Specificity

Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte. Reduced expression in breast carcinomas expressing a wild-type TP53 protein. Overexpressed in lung cancer cell lines.

Subcellular Localizations

Cytoplasm, perinuclear region. Nucleus. Predominantly found in the perinuclear region. Some small fraction is nuclear. Sequester in the cytoplasm on overexpression of DDX42.