Tensin-1 Antibodies

AND TNS1 ELISA kits, Tensin-1 Proteins

Many biological assays use antibodies to detect Tensin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tensin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tensin-1 antibodies...

We validate the specificity of these antibodies to Tensin-1 by testing them on tissues known to express TNS1 positively and negatively. Browse below to find the TNS1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TNS1 Infographic by Boster Bio

All TNS1 Products

Product

Figures

Specificity

Applications

Price

Anti-Phospho-Tensin-1 (Y1326) TNS1 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A04990Y1326
100ul

Anti-Tensin-1 TNS1 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A04990
100ul

Tensin 1 (TNS1) (NM_022648) Human Over-expression Lysate

Human

$960
Cat # LS007145
100 µg

TNS1 Overview

Facts about Tensin-1.

TNS1 3D structure. Source: alphafold

Tensin-1 (TNS1)

Involved in fibrillar adhesion formation. May be involved in cell migration, cartilage growth and in linking signal transduction pathways to the cytoskeleton.

Gene Information

Human
Gene Name:	TNS1
Uniprot:	Q9HBL0
Entrez:	7145

Family

Belongs to:

PTEN phosphatase protein family

Alternative Names

DKFZp586K0617; matrix-remodelling associated 6; Matrix-remodelling-associated protein 6; MGC88584; MST091; MST122; MST127; MSTP127; MXRA6; tensin 1; tensin; tensin-1; TNSMSTP122

Molecular Weight

Mass (kDA):
185.701 kDA

Genomic Context


Human

Location:	2q35
Sequence:	2; NC_000002.12 (217799588..218002995, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cell surface. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Localized at cell periphery preferentially to fibrillar adhesions than focal adhesions. Translocates from the cell edge to cell center in an ITGB1BP1-dependent manner.

Diseases

Lung Diseases
Lung Diseases, Obstructive
Chronic Obstructive Airway Disease
Lung Injury
Sclerosis
Myoclonic Epilepsy, Juvenile
Cleft Palate
Respiration Disorders
Epilepsy
Polycystic Kidney Diseases
Epilepsies, Myoclonic

Kidney Diseases
Cleft Lip
Glomerulosclerosis (disorder)
Acute Lung Injury
Dysequilibrium Syndrome

Interacting Proteins

Pathways

Transport
Cell Migration
Protein Catabolic Process
Protein Transport
Catabolic Process
Localization

PTMs

Phosphoprotein

Research Areas

Cell Cycle and Replication
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNS1

References

PMID: 11023826 by Chen H., et al. Molecular characterization of human tensin.

PMID: 17517630 by Qian X., et al. Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activities.