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TNFRSF10D Antibodies
AND TNFRSF10D ELISA kits, TNFRSF10D Proteins
Many biological assays use antibodies to detect TNFRSF10D, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNFRSF10D in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNFRSF10D antibodies...
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TNFRSF10D Infographic by Boster Bio
All TNFRSF10D Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK2067
96 wells/kit, with removable strips.
Cat # EK2067
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, IF, IHC-P, ICC, WB
$449
Cat # A05136-1
0.1 mg
Cat # A05136-1
0.1 mg
SDS-PAGE, Bioactivity
$265
Cat # PROTQ9UBN6
Starting from 10ug
Cat # PROTQ9UBN6
Starting from 10ug
TNFRSF10D Overview
Facts about Tumor necrosis factor receptor superfamily member 10D.
Tumor necrosis factor receptor superfamily member 10D (TNFRSF10D)
Receptor for the cytotoxic ligand TRAIL.
Includes a truncated death domain and hence isn't capable of inducing apoptosis but protects against TRAIL-mediated apoptosis.Reports are contradictory with respect to its ability to induce the NF- kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can cause the NF-kappa-B pathway.
Gene Information
| Human | |
|---|---|
| Gene Name: | TNFRSF10D |
| Uniprot: | Q9UBN6 |
| Entrez: | 8793 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD264 antigen; CD264; DcR2; DCR2decoy with truncated death domain; Decoy receptor 2; TNF receptor-related receptor for TRAIL; TNF-related apoptosis-inducing ligand receptor 4; TNFRSF10D; TRAIL R4; TRAILR4; TRAIL-R4; TRAILR4TRAIL receptor 4; TRUNDDTRAIL receptor with a truncated death domain; tumor necrosis factor receptor superfamily member 10D; tumor necrosis factor receptor superfamily, member 10d, decoy with truncateddeath domain
Molecular Weight
Mass (kDA):
41.823 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8p21.3 |
| Sequence: | 8; NC_000008.11 (23135588..23164027, complement) |
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Neuroblastoma
- Prostatic Neoplasms
- Malignant Neoplasm Of Prostate
- Adenocarcinoma
- Malignant Paraganglionic Neoplasm
- Malignant Tumor Of Colon
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Inflammation
Pathways
- Methylation
- Cell Death
- Pathogenesis
- Dna Methylation
- Sensitization
- Cell Proliferation
- Programmed Cell Death
- Cellular Senescence
- Senescence
- Gene Silencing
- Dna Hypomethylation
- Aging
- Response To Virus
PTMs
- Methylation
- Cleavage
Research Areas
- Apoptosis
- Cancer
- Cell Biology
- Cytokine Research
- Immunology
- Innate Immunity
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNFRSF10D
bosterbio.com/bosterbio-gene-info-cards/TNFRSF10D
References
PMID: 9382840 by Marsters S.A., et al. A novel receptor for Apo2L/TRAIL contains a truncated death domain.
PMID: 9430226 by Degli-Esposti M.A., et al. The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain.