TNFRSF10C Antibodies

AND TNFRSF10C ELISA kits, TNFRSF10C Proteins

Many biological assays use antibodies to detect TNFRSF10C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNFRSF10C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNFRSF10C antibodies...

We validate the specificity of these antibodies to TNFRSF10C by testing them on tissues known to express TNFRSF10C positively and negatively. Browse below to find the TNFRSF10C antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TNFRSF10C Infographic by Boster Bio

All TNFRSF10C Products

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Product

Figures

Specificity

Applications

Price

Human TRAILR3/TNFRSF10C ELISA Kit PicoKine®

6 Q&As

Human

ELISA

$499
Cat # EK0533
96 wells/kit, with removable strips.

Anti-DcR1 TNFRSF10C Antibody

Human, Mouse, Rat

ELISA, IF, ICC, WB

$449
Cat # A04218-1
0.1 mg

Human TRAIL R3/TNFRSF10C Recombinant Protein

SDS-PAGE

$250
Cat # PROTO14798
Starting from 20ug

Anti-DcR1 / CD263 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, ICC, WB

$370
Cat # M04218
100 µl/vial

TNFRSF10C Overview

Facts about Tumor necrosis factor receptor superfamily member 10C.

TNFRSF10C 3D structure. Source: alphafold

Tumor necrosis factor receptor superfamily member 10C (TNFRSF10C)

Receptor for the cytotoxic ligand TRAIL.
Lacks a cytoplasmic death domain and hence isn't capable of inducing apoptosis.

May protect cells from TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand. .

Gene Information

Human
Gene Name:	TNFRSF10C
Uniprot:	O14798
Entrez:	8794

Family

Belongs to:

No superfamily

Alternative Names

Antagonist decoy receptor for TRAIL/Apo-2L; CD263 antigen; CD263; cytotoxic TRAIL receptor-3; DcR1; DCR1MGC149502; Decoy receptor 1; Decoy TRAIL receptor without death domain; LITMGC149501; Lymphocyte inhibitor of TRAIL; TNFRSF10C; TRAIL R3; TRAIL receptor 3; TRAIL receptor without an intracellular domain; TRAILR3; TRAIL-R3; TRAILR3TNF-related apoptosis-inducing ligand receptor 3; TRIDDCR1-TNFR; tumor necrosis factor receptor superfamily member 10C; tumor necrosis factor receptor superfamily, member 10c, decoy without anintracellular domain

Molecular Weight

Mass (kDA):
27.407 kDA

Genomic Context


Human

Location:	8p21.3
Sequence:	8; NC_000008.11 (23102921..23117445)

Tissue Specificity

Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart.

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Adenocarcinoma
Leukemia
Malignant Paraganglionic Neoplasm
Neuroblastoma
Colonic Neoplasms
Leukemia, Myelocytic, Acute
Malignant Tumor Of Colon
Autoimmune Reaction
Melanoma
Ovarian Neoplasm

Myeloid Leukemia
Mammary Neoplasms
Autoimmune Diseases
Inflammation
Liver Neoplasms
Malignant Squamous Cell Neoplasm
Tumor Progression

Pathways

Cell Death
Methylation
Induction Of Apoptosis
Dna Methylation
Sensitization
Pathogenesis
Drug Resistance
Programmed Cell Death
Gene Silencing
Localization
Rna Interference
Demethylation
Cell Growth

Transport
Heterochromatin Maintenance
Hyperphosphorylation
Dna Hypomethylation
Cellular Senescence
Vasculogenesis
Regulation Of Programmed Cell Death

PTMs

Methylation
Cleavage

Phosphorylation
Demethylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNFRSF10C

References

PMID: 9325248 by MacFarlane M., et al. Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL.

PMID: 9314565 by Degli-Esposti M.A., et al. Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family.