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- Table of Contents
Facts about BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2.
Its interaction with RHOB may regulate apoptosis. May improve the PCNA-dependent DNA polymerase delta activity.
Human | |
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Gene Name: | TNFAIP1 |
Uniprot: | Q13829 |
Entrez: | 7126 |
Belongs to: |
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BACURD family |
B12; B61; BACURD2; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; BTB/POZ domain-containing protein TNFAIP1; EDP1; hBACURD2; MGC2317; Protein B12; tumor necrosis factor, alpha-induced protein 1 (endothelial); Tumor necrosis factor, alpha-induced protein 1, endothelial
Mass (kDA):
36.204 kDA
Human | |
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Location: | 17q11.2 |
Sequence: | 17; NC_000017.11 (28335671..28347009) |
Cytoplasm. Nucleus. Endosome. Colocalizes with RHOB in endosomes.
PMID: 1370465 by Wolf F.W., et al. Characterization of a novel tumor necrosis factor-alpha-induced endothelial primary response gene.
PMID: 19637314 by Kim D.M., et al. RhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cells.