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Tenascin Antibodies
AND TNC ELISA kits, Tenascin Proteins
Many biological assays use antibodies to detect Tenascin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tenascin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tenascin antibodies...
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TNC Infographic by Boster Bio
All TNC Products
Product
Figures
Specificity
Applications
Price
Human Tenascin-C/TNC ELISA Kit PicoKine®
1 Citations 6 Q&As
Human
ELISA
$450
Cat # EK1170
96 wells/kit, with removable strips.
Cat # EK1170
96 wells/kit, with removable strips.
Human
Flow Cytometry, IF, IHC
$486
Cat # M00936
100ug/vial
Cat # M00936
100ug/vial
TNC Overview
Facts about Tenascin.
Tenascin (TNC)
Extracellular matrix protein implicated in advice of migrating neurons in addition to axons during development, synaptic plasticity in addition to neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes.
Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and regeneration of endothelial cells (PubMed:19884327).
Gene Information
| Human | |
|---|---|
| Gene Name: | TNC |
| Uniprot: | P24821 |
| Entrez: | 3371 |
Family
| Belongs to: |
|---|
| tenascin family |
Alternative Names
150-225; Cytotactin; Glioma-associated-extracellular matrix antigen; GMEM; GP 150-225; hexabrachion (tenascin C, cytotactin); hexabrachion (tenascin); Hexabrachion; HXB; HXBcytotactin; JI; MGC167029; Myotendinous antigen; neuronectin; Tenascin C; Tenascin J1; tenascin; tenascin-C isoform 14/AD1/16; Tenascin-C; TNC; TN-C; TNGP
Molecular Weight
Mass (kDA):
240.853 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q33.1 |
| Sequence: | 9; NC_000009.12 (115019575..115118244, complement) |
Subcellular Localizations
Secreted, extracellular space, extracellular matrix.
Diseases
- Neoplasms
- Malignant Neoplasms
- Migraine Disorders
- Headache
- Tissue Adhesions
- Inflammation
- Graft-vs-host Disease
- Pain
- Cardiomyopathies
- Muscle Rigidity
- Neoplasm Metastasis
- Leukemia
- Malignant Paraganglionic Neoplasm
Interacting Proteins
- COL5A1
- TLR4
Pathways
- Muscle Contraction
- Regulation Of Muscle Contraction
- Cardiac Muscle Contraction
- Skeletal Muscle Contraction
- Pathogenesis
- Regeneration
- Striated Muscle Contraction
- Wound Healing
- Cell Adhesion
- Cell Migration
- Localization
- Sensitization
- Cell Proliferation
PTMs
- Phosphorylation
- Cleavage
- Reduction
- Oxidation
- Acetylation
- Nitration
Research Areas
- Breast Cancer
- Cancer
- Extracellular Matrix
- Neuroscience
- Prostate Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNC
bosterbio.com/bosterbio-gene-info-cards/TNC
References
PMID: 1704365 by Nies D.E., et al. The complete cDNA sequence of human hexabrachion (Tenascin). A multidomain protein containing unique epidermal growth factor repeats.
PMID: 1707164 by Siri A., et al. Human tenascin: primary structure, pre-mRNA splicing patterns and localization of the epitopes recognized by two monoclonal antibodies.
2 Publications of Boster Tenascin Antibodies & ELISA Kits
- PubMed ID: 10.1007/s10753-020-01226-9, Integrin-α9 and Its Corresponding Ligands Play Regulatory Roles in Chronic Peri...
- PubMed ID: 32648862, Cai J,Xie X,Li D,Wang L,Jiang J,Mo X,Zhao J.A novel knitted scaffold made of mic...
*More publications can be found for each product on its corresponding product page