TLX1 Antibodies

AND TLX1 ELISA kits, TLX1 Proteins

Many biological assays use antibodies to detect TLX1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TLX1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TLX1 antibodies...

We validate the specificity of these antibodies to TLX1 by testing them on tissues known to express TLX1 positively and negatively. Browse below to find the TLX1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TLX1 Infographic by Boster Bio

All TLX1 Products

Product

Figures

Specificity

Applications

Price

Anti-TLX1 Antibody

Human, Mouse, Rat

ELISA, IHC-P, WB

$449
Cat # A04342
0.1 mg

HOX11 (TLX1) (NM_005521) Human Over-expression Lysate

Human

$628
Cat # LS003195
100 µg

TLX1 Overview

Facts about T-cell leukemia homeobox protein 1.

TLX1 3D structure. Source: alphafold

T-cell leukemia homeobox protein 1 (TLX1)

Controls the genesis of the spleen.
Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.

Gene Information

Human
Gene Name:	TLX1
Uniprot:	P31314
Entrez:	3195

Family

Belongs to:

No superfamily

Alternative Names

homeo box 11 (T-cell lymphoma 3-associated breakpoint); homeo box-11 (T-cell leukemia-3 associated breakpoint, homologous to DrosophilaNotch); Homeobox protein Hox-11; HOX11T-cell leukemia, homeobox 1; Proto-oncogene TCL-3; T-cell leukemia homeobox 1; T-cell leukemia homeobox protein 1; T-cell leukemia/lymphoma protein 3; TCL3MGC163402

Molecular Weight

Mass (kDA):
34.365 kDA

Genomic Context


Human

Location:	10q24.31
Sequence:	10; NC_000010.11 (101130773..101137789)

Subcellular Localizations

Nucleus.

Diseases

Leukemia
Precursor T-cell Lymphoblastic Leukemia-lymphoma
Acute Lymphocytic Leukemia
Chromosomal Translocation
Adult T-cell Lymphoma/leukemia
Neoplasms
Malignant Neoplasms
Cell Transformation, Neoplastic
Leukemia, T-cell
Leukemogenesis
Cytogenetic Abnormality
Nervousness

Lymphoma
Malignant Paraganglionic Neoplasm
Aneuploidy
Dysplasia
Hypoventilation
Congenital Central Hypoventilation
Acute Erythroblastic Leukemia

Interacting Proteins

Ets1
MEIS1

Pathways

Pathogenesis
Spleen Development
Cell Differentiation
Oncogenesis
Cell Proliferation
Methylation
Cell Maturation
Regeneration
V(d)j Recombination
Cell Cycle
Localization
Cell Death
Cell Growth

Interphase
T Cell Differentiation
Organ Development
Innervation
Transport
Immune Response
Mitosis

PTMs

Methylation
Phosphorylation
Biotinylation

Demethylation
Cleavage
Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TLX1

References

PMID: 1717256 by Lu M., et al. The tcl-3 proto-oncogene altered by chromosomal translocation in T- cell leukemia codes for a homeobox protein.

PMID: 1681546 by Kennedy M.A., et al. HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24.