Toll-like receptor 7 Antibodies

AND TLR7 ELISA kits, Toll-like receptor 7 Proteins

Many biological assays use antibodies to detect Toll-like receptor 7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Toll-like receptor 7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Toll-like receptor 7 antibodies...

We validate the specificity of these antibodies to Toll-like receptor 7 by testing them on tissues known to express TLR7 positively and negatively. Browse below to find the TLR7 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TLR7 Infographic by Boster Bio

All TLR7 Products

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Specificity

Applications

Price

Anti-TLR7 Antibody Picoband®

1 Citations 16 Q&As

Human, Mouse, Rat

Flow Cytometry, IHC, ICC, WB

$370
Cat # PB9452
100 μg/vial

Anti-Toll-like receptor 7 TLR7 Antibody Picoband®

17 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # PA1733
100 μg/vial

Anti-TLR7 Rabbit Monoclonal Antibody

4 Q&As

Human

IHC, WB

$370
Cat # M00376
100 μl

TLR7 Overview

Facts about Toll-like receptor 7.

TLR7 3D structure. Source: alphafold

Toll-like receptor 7 (TLR7)

Key part of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to germs.

TLR7 is a nucleotide-sensing TLR that's triggered by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

Gene Information

Human
Gene Name:	TLR7
Uniprot:	Q9NYK1
Entrez:	51284

Family

Belongs to:

Toll-like receptor family

Alternative Names

TLR7; toll-like receptor 7

Molecular Weight

Mass (kDA):
120.922 kDA

Genomic Context


Human

Location:	Xp22.2
Sequence:	X; NC_000023.11 (12867072..12890361)

Tissue Specificity

Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells.

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.

Diseases

Virus Diseases
Inflammation
Infective Disorder
Innate Immune Response
Autoimmune Reaction
Malignant Neoplasms
Neoplasms
Lupus Erythematosus, Systemic
Autoimmune Diseases
Influenza
Autoimmunity
Hiv Infections
Hepatitis

Inflammatory Response
Hepatitis C
Carcinoma
Asthma
Melanoma
Communicable Diseases
Immunologic Deficiency Syndromes

Pathways

Immune Response
Secretion
Cytokine Production
Pathogenesis
Innate Immune Response
Cell Activation
Inflammatory Response
Cell Proliferation
Viral Replication
Localization
Cytokine Secretion
Adaptive Immune Response
Rna Interference

Phagocytosis
Cell Death
Cell Differentiation
Sensitization
Type I Interferon Production
B Cell Activation
B Cell Proliferation

PTMs

Phosphorylation
Methylation
Phosphorothioation
Cleavage
Ubiquitination
Glycosylation

Reduction
Oxidation
Sumoylation
Hydroxylation
Amidation
Acetylation

Research Areas

Cytokine Research
Immunology
Innate Immunity

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TLR7

References

PMID: 11022119 by Du X., et al. Three novel mammalian Toll-like receptors: gene structure, expression, and evolution.

PMID: 11022120 by Chuang T.-H., et al. Cloning and characterization of a sub-family of human Toll-like receptors: hTLR7, hTLR8 and hTLR9.

1 Publications of Boster Toll-like receptor 7 Antibodies & ELISA Kits

PubMed ID: 29561265, Esancy K, Condon L, Feng J, Kimball C, Curtright A, Dhaka A. Elife. 2018 Mar 21;...

*More publications can be found for each product on its corresponding product page