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Toll-like receptor 2 Antibodies
AND TLR2 ELISA kits, Toll-like receptor 2 Proteins
Many biological assays use antibodies to detect Toll-like receptor 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Toll-like receptor 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Toll-like receptor 2 antibodies...
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TLR2 Infographic by Boster Bio
All TLR2 Products
Product
Figures
Specificity
Applications
Price
Human TLR2/Toll-like receptor 2 ELISA Kit PicoKine®
2 Citations 9 Q&As
Human
ELISA
$499
Cat # EK0906
96 wells/kit, with removable strips.
Cat # EK0906
96 wells/kit, with removable strips.
Mouse TLR2/Toll-like receptor 2 ELISA Kit PicoKine®
1 Citations 9 Q&As
Mouse
ELISA
$499
Cat # EK1130
96 wells/kit, with removable strips.
Cat # EK1130
96 wells/kit, with removable strips.
Anti-TLR2 Rabbit Monoclonal Antibody
5 Citations 17 Q&As
Human, Mouse, Rat
WB
$370
Cat # M00131
100 μl
Cat # M00131
100 μl
Anti-Toll-like receptor 2 TLR2 Antibody
1 Citations
Human, Mouse
ELISA, IF, IHC-P, WB
$449
Cat # A00131-1
0.1 mg
Cat # A00131-1
0.1 mg
Anti-Toll-like receptor 2 TLR2 Antibody
1 Citations
Human, Mouse, Rat
IF, ICC, WB
$405
Cat # A00131-3
100ul
Cat # A00131-3
100ul
TLR2 Overview
Facts about Toll-like receptor 2.
Toll-like receptor 2 (TLR2)
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed:21078852, PubMed:17889651).
Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also activate immune cells and promote apoptosis in response to the lipid moiety of lipoproteins (PubMed:10426995, PubMed:10426996).
Gene Information
| Human | |
|---|---|
| Gene Name: | TLR2 |
| Uniprot: | O60603 |
| Entrez: | 7097 |
Family
| Belongs to: |
|---|
| Toll-like receptor family |
Alternative Names
CD282 antigen; CD282; TIL4CD282; TLR2; toll/interleukin 1 receptor-like 4; Toll/interleukin-1 receptor-like protein 4; toll-like receptor 2
Molecular Weight
Mass (kDA):
89.838 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q31.3 |
| Sequence: | 4; NC_000004.12 (153684080..153710643) |
Tissue Specificity
Highly expressed in peripheral blood leukocytes, in particular in monocytes, in bone marrow, lymph node and in spleen. Also detected in lung and in fetal liver. Levels are low in other tissues.
Subcellular Localizations
Membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein. Membrane raft. Does not reside in lipid rafts before stimulation but accumulates increasingly in the raft upon the presence of the microbial ligand. In response to diacylated lipoproteins, TLR2:TLR6 heterodimers are recruited in lipid rafts, this recruitment determines the intracellular targeting to the Golgi apparatus. Triacylated lipoproteins induce the same mechanism for TLR2:TLR1 heterodimers.
Diseases
- Inflammation
- Innate Immune Response
- Infective Disorder
- Inflammatory Response
- Pneumonia
- Bacterial Infections
- Tuberculosis
- Systemic Infection
- Malignant Neoplasms
- Atherosclerosis
- Neoplasms
- Arthritis
- Tissue Adhesions
Interacting Proteins
- CXCR4
- EGFR
- MYD88
- TLR1
- TLR10
- TLR6
Pathways
- Immune Response
- Secretion
- Cytokine Production
- Pathogenesis
- Inflammatory Response
- Innate Immune Response
- Cell Activation
- Phagocytosis
- Virulence
- Cytokine Secretion
- Cell Proliferation
- Cell Death
- Macrophage Activation
PTMs
- Phosphorylation
- Methylation
- Cleavage
- Acylation
- Acetylation
- Oxidation
- Ubiquitination
- Glycosylation
- Dephosphorylation
- Biotinylation
Research Areas
- Immunology
- Innate Immunity
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TLR2
bosterbio.com/bosterbio-gene-info-cards/TLR2
Best Uses Of The TLR2 Marker
Boster Bio is a fantastic tool to optimize your experiments. There are numerous optimization techniques and guides available to guide your decisions and aid you in improving your results. Every experiment isn't simple. The good news is that the majority of the mistakes can be avoided by using appropriate controls. Troubleshooting guides can assist you in identifying and fixing any issues you encounter with your Boster Bio experiment.
Boster Bio Anti-Versican/VCAN Antibody Picoband
The Anti-Versican/VCAN antibody from Boster Bio is designed for use with ELISA and IHC systems. The 12,000+ antibodies in Boster Bio's Anti-Versican/VCAN antibody range have been tested against panels from over 250 tissues to ensure the highest level of specificity and affinity. Each of Boster's antibodies has been tested quantitatively against known amounts of recombinant protein to ensure they are effective in both quantitative and qualitative tests for immunoassays. Boster's products have undergone extensive testing and are backed by technical support and an experienced customer service team.
The Boster Bio Anti-Versican (VCAN) Antibody Picoband recognizes Human, Mouse, and Rat antigens. It is also suitable for use in immunohistochemistry. Its excellent immunocytochemical performance has been validated for Western Blot and Immunohistochemistry. For more information, please visit the company's website. A Sanbio representative Sanbio will be happy to answer any questions you may have.
References
PMID: 9596645 by Chaudhary P.M., et al. Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans.
PMID: 9435236 by Rock F.L., et al. A family of human receptors structurally related to Drosophila Toll.
19 Publications of Boster Toll-like receptor 2 Antibodies & ELISA Kits
- PubMed ID: 10.3892/ol.2014.2621, Upregulation of Toll‑like receptor 2 expression in colorectal cancer infected...
- PubMed ID: 10.3892/mmr.2017.8010, HuR induces inflammatory responses in HUVECs and murine sepsis via binding to HM...
- PubMed ID: 10.3389/fncel.2017.00099, Phospholipase A2 of Peroxiredoxin 6 Plays a Critical Role in Cerebral Ischemia/R...
- PubMed ID: 10.1186/1743-422X-10-40, A novel DNA vaccine expressing the Ag85A-HA2 fusion protein provides protection ...
- PubMed ID: 10.1128/AEM.01636-21, Protective Effects of Selenium Nanoparticle-Enriched Lactococcus lactis NZ9000 a...
- PubMed ID: 10.1111/jphp.12402, Shikonin inhibits the cell viability, adhesion, invasion and migration of the hu...
- PubMed ID: 10.1038/s41467-021-25340-w, Oral immune dysfunction is associated with the expansion of FOXP3+PD-1+Amphiregu...
- PubMed ID: 10.1016/j.molimm.2017.08.022, Effect of lentivirus-mediated gene silencing, targeting toll-like receptor 2, on...
- PubMed ID: 10.1016/j.ijbiomac.2016.05.002, Bletilla striata polysaccharide inhibits angiotensin II-induced ROS and inflamma...
- PubMed ID: 10.1002/ar.23463, Expression of TLR2/4 on Epididymal Spermatozoa of the Chinese Soft‐Shelled Tur...
- PubMed ID: 10.1002/ar.23463, Expression of TLR2/4 on Epididymal Spermatozoa of the Chinese Soft‐Shelled Tur...
- PubMed ID: 10.1002/ar.23463, Expression of TLR2/4 on Epididymal Spermatozoa of the Chinese Soft‐Shelled Tur...
- PubMed ID: 31857223, Shi Y,Vistro WA,Bai X,Wu R,Chen C,Huang Y,Fazlani SA,Tarique I,Yang P,Chen Q.Eff...
- PubMed ID: 32801828, Feng S,Ju L,Shao Z,Grzanna M,Jia L,Liu M.Therapeutic Effect of C-C Chemokine Rec...
- PubMed ID: 27532861, Expression of TLR2/4 on Epididymal Spermatozoa of the Chinese Soft%u2010Shelled ...
- PubMed ID: 27340562, Inhibition of Zymosan-Induced Inflammatory Factors Expression by ATRA Nanostruct...
- PubMed ID: 23369570, A novel DNA vaccine expressing the Ag85A-HA2 fusion protein provides protection ...
- PubMed ID: 24460643, Wang Y, Ge P, Yang L, Wu C, Zha H, Luo T, Zhu Y. J Neuroinflammation. 2014 Jan 2...
- PubMed ID: 25435993, Li X, Qian D, Ju F, Wang B. Oncol Lett. 2015 Jan;9(1):365-370. Epub 2014 Oct 15....
*More publications can be found for each product on its corresponding product page