Talin-1 Antibodies

AND TLN1 ELISA kits, Talin-1 Proteins

Many biological assays use antibodies to detect Talin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Talin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Talin-1 antibodies...

We validate the specificity of these antibodies to Talin-1 by testing them on tissues known to express TLN1 positively and negatively. Browse below to find the TLN1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TLN1 Infographic by Boster Bio

All TLN1 Products

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Specificity

Applications

Price

Anti-Talin 1/TLN1 Antibody Picoband®

2 Citations 7 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # A02859-1
100 μg/vial

Anti-Talin 1/TLN1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A02859-2
100 μg/vial

Anti-Talin 1/TLN1 Antibody Picoband® (monoclonal, 2G10D2)

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # M02859
100 μg/vial

TLN1 Overview

Facts about Talin-1.

TLN1 3D structure. Source: alphafold

Talin-1 (TLN1)

Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell connections (By similarity).

. .

Gene Information

Human
Gene Name:	TLN1
Uniprot:	Q9Y490
Entrez:	7094

Family

Belongs to:

No superfamily

Alternative Names

ILWEQ; KIAA1027; talin 1; Talin1; talin-1; TLN; TLN1

Molecular Weight

Mass (kDA):
269.767 kDA

Genomic Context


Human

Location:	9p13.3
Sequence:	9; NC_000009.12 (35696948..35732195, complement)

Subcellular Localizations

Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell surface. Cell junction, focal adhesion. Colocalizes with LAYN at the membrane ruffles. Localized preferentially in focal adhesions than fibrillar adhesions (By similarity).

Diseases

Tissue Adhesions
Neoplasms
Malignant Neoplasms
Carcinoma
Cell Invasion
Neoplasm Metastasis
Neoplasm Invasiveness
Cell Transformation, Neoplastic
Mouth Neoplasms
Mammary Neoplasms
Ovarian Neoplasm
Liver Carcinoma
Prostatic Neoplasms

Liver Neoplasms
Tumor Progression
Carcinogenesis
Malignant Neoplasm Of Ovary
Malignant Neoplasm Of Prostate
Malignant Squamous Cell Neoplasm
Angiomatosis, Bacillary

Interacting Proteins

EGFR
ERBB2
ITGB1
ITGB3

Pathways

Cell Adhesion
Integrin Activation
Proteolysis
Cell Cycle
Rna Interference
Cell Migration
Localization
Cell Motility
Cell Differentiation
Cell Growth
Focal Adhesion Assembly
Secretion
Regulation Of Binding

Endocytosis
Cell Fate Specification
Cytokinesis
Chemotaxis
Swimming
Mrna Splicing
Anoikis

PTMs

Phosphorylation

Cleavage

Ubiquitination

Research Areas

Cell Biology
Cellular Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TLN1

References

PMID: 10610730 by Ben-Yosef T., et al. Characterization of the human talin (TLN) gene: genomic structure, chromosomal localization, and expression pattern.

PMID: 10320340 by Luo G., et al. Molecular interactions of N-RAP, a nebulin-related protein of striated muscle myotendon junctions and intercalated disks.

2 Publications of Boster Talin-1 Antibodies & ELISA Kits

PubMed ID: 10.1096/fj.201801949RR, Talin promotes integrin activation accompanied by generation of tension in talin...
PubMed ID: 32742451, Song Y,Li C,Fu Y,Xie Q,Guo J,Li G,Wu H.Inward Tension of Talin and Integrin-rela...

*More publications can be found for each product on its corresponding product page