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Thrombopoietin Antibodies
AND THPO ELISA kits, Thrombopoietin Proteins
Many biological assays use antibodies to detect Thrombopoietin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Thrombopoietin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Thrombopoietin antibodies...
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THPO Infographic by Boster Bio
All THPO Products
Product
Figures
Specificity
Applications
Price
Mouse Thrombopoietin/TPO ELISA Kit PicoKine®
3 Citations 6 Q&As
Mouse
ELISA
$499
Cat # EK0517
96 wells/kit, with removable strips.
Cat # EK0517
96 wells/kit, with removable strips.
Mouse, Rat
ELISA, IHC, WB
$370
Cat # A03222-1
100 μg/vial
Cat # A03222-1
100 μg/vial
SDS-PAGE, Bioactivity
$287
Cat # PROTP40226
Starting from 10ug
Cat # PROTP40226
Starting from 10ug
THPO Overview
Facts about Thrombopoietin.
Thrombopoietin (THPO)
Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes in their committed progenitor cells. It acts at a late period of megakaryocyte development.
It might be the major physiological regulator of circulating platelets. .
Gene Information
| Human | |
|---|---|
| Gene Name: | THPO |
| Uniprot: | P40225 |
| Entrez: | 7066 |
Family
| Belongs to: |
|---|
| EPO/TPO family |
Alternative Names
Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; megakaryocyte stimulating factor; MGDF; MGDFC-mpl ligand; MKCSF; MK-CSF; ML; MPL ligand; MPLLG; MPLLGMGC163194; Myeloproliferative leukemia virus oncogene ligand; THCYT1; THPO; thrombopoietin nirs variant 1; Thrombopoietin; Tpo; TPOMKCSF
Molecular Weight
Mass (kDA):
37.823 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3q27.1 |
| Sequence: | 3; NC_000003.12 (184371935..184379688, complement) |
Subcellular Localizations
Secreted.
Diseases
- Thrombocytosis
- Leukemia
- Myeloid Leukemia
- Malignant Neoplasms
- Neoplasms
- Epilepsy
- Leukemia, Myelocytic, Acute
- Myeloproliferative Disease
- Thrombocythemia, Essential
- Aplastic Anemia
- Anemia
- Pain
Pathways
- Transport
- Cell Adhesion
- Pathogenesis
- Chloride Transport
- Dna Repair
- Regulation Of Gene Expression
- Vasculogenesis
- Megakaryocyte Development
- Localization
- Transepithelial Transport
PTMs
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/THPO
bosterbio.com/bosterbio-gene-info-cards/THPO
References
PMID: 8202154 by de Sauvage F.J., et al. Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand.
PMID: 8020099 by Bartley T.D., et al. Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl.
3 Publications of Boster Thrombopoietin Antibodies & ELISA Kits
- PubMed ID: 10.1096/fj.201902142R, Deficiency of platelet adhesion molecule CD226 causes megakaryocyte development ...
- PubMed ID: 10.1080/08923973.2017.1392564, Improvement of icaritin on hematopoietic function in cyclophosphamide-induced my...
- PubMed ID: 27378920, Extracted Triterpenes from Antrodia cinnamomea Reduce the Inflammation to Promot...
*More publications can be found for each product on its corresponding product page