TFCP2 Antibodies

AND TFCP2 ELISA kits, TFCP2 Proteins

Many biological assays use antibodies to detect TFCP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TFCP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TFCP2 antibodies...

We validate the specificity of these antibodies to TFCP2 by testing them on tissues known to express TFCP2 positively and negatively. Browse below to find the TFCP2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TFCP2 Infographic by Boster Bio

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Anti-TFCP2 Antibody

Human, Mouse

$405
Cat # A05548
100ul

TFCP2 Overview

Facts about Alpha-globin transcription factor CP2.

TFCP2 3D structure. Source: alphafold

Alpha-globin transcription factor CP2 (TFCP2)

Binds an assortment of viral and cellular promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity).

Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells.

Gene Information

Human
Gene Name:	TFCP2
Uniprot:	Q12800
Entrez:	7024

Family

Belongs to:

grh/CP2 family

Alternative Names

alpha-globin transcription factor CP2; CP2; LBP-1C; LSF1D; LSFLBP1C; SAA3 enhancer factor; SEF; TFCP2C; transcription factor CP2; Transcription factor LSF

Molecular Weight

Mass (kDA):
57.256 kDA

Genomic Context


Human

Location:	12q13.12-q13.13
Sequence:	12; NC_000012.12 (51093656..51173135, complement)

Tissue Specificity

Ubiquitous. Expressed in brain, ovary, kidney, thymus, spleen, liver, adrenal, heart and lung (at protein level).

Subcellular Localizations

Nucleus.

Diseases

Alzheimer's Disease
Carcinoma
Neoplasms
Hiv Infections
Liver Carcinoma
Neoplasm Metastasis
Immunologic Deficiency Syndromes
Malignant Neoplasms
Liver Neoplasms
Tumor Angiogenesis
Cell Invasion
Hepatocarcinogenesis

Cell Transformation, Neoplastic
Nerve Degeneration
Adenocarcinoma
Acute Erythroblastic Leukemia
Neurotoxicity Syndromes
Neuroendocrine Tumors

Pathways

Pathogenesis
Cell Cycle
Angiogenesis
Cell Death
Transport
Oncogenesis
Localization
Senescence
Dna Replication
Cell Growth
Virulence
Nuclear Export
Inflammatory Response

Cell Division
Mrna Splicing
Translation
Chromatin Modification
Segmentation
Histone Deacetylation
Cell Proliferation

PTMs

Phosphorylation
Cleavage
Dephosphorylation
Sumoylation

Glycosylation
Deacetylation
Acetylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TFCP2

References

PMID: 1732747 by Lim L.C., et al. Molecular cloning of the alpha-globin transcription factor CP2.

PMID: 8114710 by Yoon J.-B., et al. Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro.