Teneurin-3 Antibodies

AND Tenm3 ELISA kits, Teneurin-3 Proteins

Many biological assays use antibodies to detect Teneurin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Teneurin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Teneurin-3 antibodies...

We validate the specificity of these antibodies to Teneurin-3 by testing them on tissues known to express Tenm3 positively and negatively. Browse below to find the Tenm3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Anti-Teneurin-3 TENM3 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A10047
0.1 mg

Tenm3 Overview

Facts about Teneurin-3.

Teneurin-3 (Tenm3)

Involved in neural development by regulating the institution of appropriate connectivity within the nervous system (PubMed:17478416, PubMed:17803360, PubMed:23028443, PubMed:25406022, PubMed:22499796, PubMed:29414938). Acts in both pre- and postsynaptic neurons in the hippocampus to control the assembly of a precise topographic projection: required in both CA1 and subicular neurons for the precise targeting of proximal CA1 axons to distal subiculum, probably by promoting homophilic cell adhesion (PubMed:29414938).

Promotes homophilic adhesion at a splicing isoform-dependent manner: most isoforms (isoform-type A and type-B) can mediate homophilic interaction (PubMed:29414938). Promotes axon guidance (PubMed:23028443).

Gene Information

Mouse
Gene Name:	Tenm3
Uniprot:	Q9WTS6
Entrez:	23965

Family

Belongs to:

tenascin family

Alternative Names

FLJ10474; FLJ10886; KIAA1455odd Oz/Ten-m homolog 3; odz, odd Oz/ten-m homolog 3 (Drosophila); ODZ3-like protein; Protein Odd Oz/ten-m homolog 3; ten-3; tenascin-M3; teneurin-3; Ten-m3; TNM3

Molecular Weight

Mass (kDA):
303.066 kDA

Genomic Context


Mouse

Location:	8\|8 B1.1-B1.2
Sequence:	8;

Tissue Specificity

In brain, expressed in highly specific regions of the postnatal brain: expressed in restricted domains of the developing hippocampal region, including proximal CA1, distal subiculum, and medial entorhinal cortex (at protein level) (PubMed:29414938). Expression matches with topographic connectivity between entorhinal cortex, CA1, and subiculum (at protein level) (PubMed:29414938). Also specifically expressed in subregions of the presubiculum, parasubiculum, medial mammillary nucleus and anteroventral thalamic nucleus that are topographically connected with subiculum or entorhinal cortex (at protein level) (PubMed:29414938). Expressed in neurons of the developing visual pathway (at protein level). Expressed in the dorsal and ventral lateral geniculate nucleus (dLGN and vLGN) and optic tract at birth. Expressed in ipsilateral retinal axons of terminal zones (TZs) in the developing superior colliculus (SC) throughout the first postnatal week. Expressed in the layer V of the visual caudal cortex. Expressed in the femoral and mandibular condylar cartilages. Strongly expressed in fibrous and proliferating chondrocytes. Poorly expressed in mature chondrocytes. Not expressed in hypertrophic

Diseases

Hypertrophy
Tissue Adhesions

PTMs

Disulfide bond

Glycoprotein

Research Areas

Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Tenm3

References

PMID: 10225957 by Oohashi T., et al. Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.

PMID: 10625539 by Ben-Zur T., et al. The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles.