Trichohyalin Antibodies

AND TCHH ELISA kits, Trichohyalin Proteins

Many biological assays use antibodies to detect Trichohyalin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Trichohyalin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Trichohyalin antibodies...

We validate the specificity of these antibodies to Trichohyalin by testing them on tissues known to express TCHH positively and negatively. Browse below to find the TCHH antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TCHH Infographic by Boster Bio

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Anti-Trichohyalin TCHH Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A10369
100ul

TCHH Overview

Facts about Trichohyalin.

TCHH 3D structure. Source: alphafold

Trichohyalin (TCHH)

Intermediate filament-associated protein that associates in regular arrays with keratin intermediate filaments (KIF) of the inner root sheath cells of the hair follicle and the granular layer of the skin. It later becomes cross-linked into KIF by isodipeptide bonds.

It can serve as scaffold protein, together with involucrin, in the organization of the cell envelope or even anchor the cell envelope to the KIF network. It can be involved in its calcium-dependent postsynthetic processing during terminal differentiation.

Gene Information

Human
Gene Name:	TCHH
Uniprot:	Q07283
Entrez:	7062

Family

Belongs to:

S100-fused protein family

Alternative Names

Trichohyalin

Molecular Weight

Mass (kDA):
253.925 kDA

Genomic Context


Human

Location:	1q21.3
Sequence:	1; NC_000001.11 (152106317..152115454, complement)

Tissue Specificity

Found in the hard keratinizing tissues such as the inner root sheath (IRS) of hair follicles and medulla, and in the filiform papillae of dorsal tongue epithelium.

PTMs

Citrullination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TCHH

References

PMID: 7685034 by Lee S.-C., et al. The structure of human trichohyalin. Potential multiple roles as a functional EF-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross- linking) protein.

PMID: 7686953 by O'Keefe E.J., et al. Trichohyalin: a structural protein of hair, tongue, nail, and epidermis.