Transcription factor 21 Antibodies

AND TCF21 ELISA kits, Transcription factor 21 Proteins

Many biological assays use antibodies to detect Transcription factor 21, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transcription factor 21 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transcription factor 21 antibodies...

We validate the specificity of these antibodies to Transcription factor 21 by testing them on tissues known to express TCF21 positively and negatively. Browse below to find the TCF21 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TCF21 Infographic by Boster Bio

All TCF21 Products

Product

Figures

Specificity

Applications

Price

TCF21 (NM_198392) Human Recombinant Protein

$1249
Cat # PROTO43680
20 µg

Anti-TCF21 Rabbit Monoclonal Antibody

Human

Flow Cytometry, IP, WB

$370
Cat # M05375
100 μl/vial

TCF21 (NM_198392) Human Over-expression Lysate

Human

$628
Cat # LS006943
100 µg

TCF21 Overview

Facts about Transcription factor 21.

TCF21 3D structure. Source: alphafold

Transcription factor 21 (TCF21)

Involved in epithelial-mesenchymal interactions in lung and kidney morphogenesis that include epithelial differentiation and branching morphogenesis. May play a role in the specification or differentiation of one or more subsets of epicardial cell types.

Gene Information

Human
Gene Name:	TCF21
Uniprot:	O43680
Entrez:	6943

Family

Belongs to:

No superfamily

Alternative Names

bHLHa23BHLHA23; Capsulin; Class A basic helix-loop-helix protein 23; epicardin; Pod-1; POD1pod-1; Podocyte-expressed 1; TCF-21; transcription factor 21

Molecular Weight

Mass (kDA):
19.715 kDA

Genomic Context


Human

Location:	6q23.2
Sequence:	6; NC_000006.12 (133889113..133895537)

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Malignant Neoplasm Of Lung
Malignant Squamous Cell Neoplasm
Lung Neoplasms
Renal Cell Carcinoma
Congenital Abnormality
Head And Neck Neoplasms
Kidney Diseases
Diabetic Nephropathy
Renal Glomerular Disease
Adenocarcinoma

Conventional (clear Cell) Renal Cell Carcinoma
Hydronephrosis
Cytogenetic Abnormality
Kidney Failure
Cardiomyopathy, Dilated
Cardiomyopathies
Sensorineural Hearing Loss (disorder)

Pathways

Methylation
Cell Differentiation
Dna Methylation
Cell Proliferation
Kidney Development
Localization
Sertoli Cell Differentiation
Gene Silencing
Cell Fate Determination
Sex Determination
Segmentation
Regeneration
Cell Growth

Dna Hypermethylation
Immune Response
Lung Development
Neurogenesis
Kidney Morphogenesis
Cell Fate Specification
Muscle Attachment

PTMs

Methylation
Demethylation

Sumoylation
Phosphorylation

Cleavage

Research Areas

Cancer
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TCF21

References

PMID: 9733105 by Robb L., et al. Epicardin: a novel basic helix-loop-helix transcription factor gene expressed in epicardium, branchial arch myoblasts, and mesenchyme of developing lung, gut, kidney, and gonads.

PMID: 10572052 by Quaggin S.E., et al. The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis.