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- Table of Contents
Facts about Taste receptor type 2 member 38.
The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). .
Human | |
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Gene Name: | TAS2R38 |
Uniprot: | P59533 |
Entrez: | 5726 |
Belongs to: |
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G-protein coupled receptor T2R family |
PTCphenylthiocarbamide tasting; T2R38; T2R61PTC bitter taste receptor; taste receptor type 2 member 38; Taste receptor type 2 member 61; taste receptor, type 2, member 38
Mass (kDA):
37.892 kDA
Human | |
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Location: | 7q34 |
Sequence: | 7; NC_000007.14 (141972631..141973773, complement) |
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Expressed in testis (PubMed:16720576).
Membrane; Multi-pass membrane protein.
PMID: 12379855 by Bufe B., et al. The human TAS2R16 receptor mediates bitter taste in response to beta- glucopyranosides.
PMID: 12584440 by Conte C., et al. Identification and characterization of human taste receptor genes belonging to the TAS2R family.