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- Table of Contents
Facts about TATA box-binding protein-associated factor RNA polymerase I subunit C.
SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
Human | |
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Gene Name: | TAF1C |
Uniprot: | Q15572 |
Entrez: | 9013 |
Belongs to: |
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No superfamily |
MGC:39976; RNA polymerase I-specific TBP-associated factor 110 kDa; SL1, 110kD subunit; SL1TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD; TAFI110TBP-associated factor 1C; TAFI95; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; TATA box-binding protein-associated factor 1C; TATA box-binding protein-associated factor RNA polymerase I subunit C; transcription factor SL1; Transcription initiation factor SL1/TIF-IB subunit C
Mass (kDA):
95.213 kDA
Human | |
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Location: | 16q24.1 |
Sequence: | 16; NC_000016.10 (84177847..84187070, complement) |
Nucleus.
PMID: 7801123 by Comai L., et al. Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits.
PMID: 10913176 by Zhai W., et al. Repression of RNA polymerase I transcription by the tumor suppressor p53.