This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Substance-P receptor.
The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. .
Human | |
---|---|
Gene Name: | TACR1 |
Uniprot: | P25103 |
Entrez: | 6869 |
Belongs to: |
---|
G-protein coupled receptor 1 family |
NK1R; NK-1R; NK1Rneurokinin 1 receptor; NKIR; SPR; SPRsubstance-P receptor; TAC1R; TAC1Rtachykinin 1 receptor (substance P receptor, neurokinin 1 receptor); tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor); tachykinin receptor 1NK-1 receptor; TACR1
Mass (kDA):
46.251 kDA
Human | |
---|---|
Location: | 2p12 |
Sequence: | 2; NC_000002.12 (75046463..75199520, complement) |
Cell membrane; Multi-pass membrane protein.
PMID: 1718267 by Takeda Y., et al. Molecular cloning, structural characterization and functional expression of the human substance P receptor.
PMID: 1659396 by Hopkins B., et al. Isolation and characterisation of the human lung NK-1 receptor cDNA.