SRMS Antibodies

AND SRMS ELISA kits, SRMS Proteins

Many biological assays use antibodies to detect SRMS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SRMS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SRMS antibodies...

We validate the specificity of these antibodies to SRMS by testing them on tissues known to express SRMS positively and negatively. Browse below to find the SRMS antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SRMS Infographic by Boster Bio

All SRMS Products

Product

Figures

Specificity

Applications

Price

Anti-Tyrosine-protein kinase Srms SRMS Antibody

Human

ELISA, WB

$380
Cat # A06352
100ul

Anti-Mouse Srms Antibody (Center)

Mouse

IF, WB

$298
Cat # A06352-1
80 µl

SRMS (NM_080823) Human Over-expression Lysate

Human

$960
Cat # LS006725
100 µg

SRMS Overview

Facts about Tyrosine-protein kinase Srms.

SRMS 3D structure. Source: alphafold

Tyrosine-protein kinase Srms (SRMS)

Non-receptor tyrosine-protein kinase that phosphorylates DOK1 on tyrosine residues (PubMed:23822091). Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues (PubMed:29496907).

Phosphorylation of KHDRBS1 is EGF-dependent (PubMed:29496907). .

Gene Information

Human
Gene Name:	SRMS
Uniprot:	Q9H3Y6
Entrez:	6725

Family

Belongs to:

protein kinase superfamily

Alternative Names

tyrosine-protein kinase Srms; C20orf148; dJ697K14.1; src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites; SRM

Molecular Weight

Mass (kDA):
54.507 kDA

Genomic Context


Human

Location:	20q13.33
Sequence:	20; NC_000020.11 (63539924..63547504, complement)

Tissue Specificity

Highly expressed in most breast cancers (at protein level).

Subcellular Localizations

Cytoplasm. Localizes to punctate cytoplasmic structures.

Diseases

Malignant Neoplasms
Neoplasms
Epilepsy, Temporal Lobe
Epilepsy
Convulsive Seizures
Pain
Depressive Disorder
Chronic Pain
Status Epilepticus
Nerve Degeneration
Nausea
Metaplasia

Embryonal Carcinoma
Melanoma
Malignant Neoplasm Of Breast
Confusion
Constipation
Mammary Neoplasms
Intestinal Metaplasia Of Gastric Mucosa

Interacting Proteins

DOK1

Pathways

Cell Differentiation
Regulation Of Epithelial Cell Differentiation
Neurogenesis
Epithelial Cell Differentiation

PTMs

Phosphorylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SRMS

References

PMID: 23822091 by Goel R.K., et al. The unique N-terminal region of SRMS regulates enzymatic activity and phosphorylation of its novel substrate Dok1.

PMID: 29496907 by Goel R.K., et al. Phosphoproteomics analysis identifies novel candidate substrates of the non-receptor tyrosine kinase, SRMS.