Slc22a12 Antibodies

AND Slc22a12 ELISA kits, Slc22a12 Proteins

Many biological assays use antibodies to detect Slc22a12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Slc22a12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Slc22a12 antibodies...

We validate the specificity of these antibodies to Slc22a12 by testing them on tissues known to express Slc22a12 positively and negatively. Browse below to find the Slc22a12 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Slc22a12 Infographic by Boster Bio

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SLC22A12 (NM_144585) Human Over-expression Lysate

Human

$628
Cat # LS116085
100 µg

Slc22a12 Overview

Facts about Solute carrier family 22 member 12.

Solute carrier family 22 member 12 (Slc22a12)

Required for efficient urate re-absorption from the kidney. Regulates blood urate levels.

Mediates saturable urate uptake by facilitating the exchange of urate against organic anions or chloride ions. .

Gene Information

Mouse
Gene Name:	Slc22a12
Uniprot:	Q8CFZ5
Entrez:	20521

Family

Belongs to:

major facilitator (TC 2.A.1) superfamily

Alternative Names

OATL4; Organic anion transporter 4-like protein; Renal-specific transporter; RSTmember 12; solute carrier family 22 (organic anion/urate transporter), member 12; URAT1; URAT1Urate anion exchanger 1; urate transporter 1

Molecular Weight

Mass (kDA):
60.194 kDA

Genomic Context


Mouse

Location:	19\|19 A
Sequence:	19;

Tissue Specificity

Detected in kidney (at protein level). Detected in kidney cortex, in proximal tubules.

Diseases

Hyperuricemia
Hypouricaemia
Gout
Familial Renal Hypouricemia
Kidney Failure
Kidney Diseases
Kidney Failure, Acute
Acute Kidney Injury
Cardiovascular Diseases
Hypertensive Disease
Urolithiasis
Nephrolithiasis
Hereditary Diseases

Primary Gout
Dysequilibrium Syndrome
Injury To Kidney
Pain
Diabetes Mellitus
Metabolic Syndrome X
Cholangiocarcinoma

Pathways

Excretion
Transport
Urate Transport
Secretion
Localization
Pathogenesis
Glomerular Filtration
Dna Methylation
Methylation
Secretory Pathway
Transmembrane Transport
Gene Silencing
Anion Transport

Glycosylation
Organic Anion Transport
Conjugation
Transepithelial Transport
Neuroprotection
Reverse Transcription
Mrna Transcription

PTMs

Carboxylation
Methylation

Biotinylation
Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Slc22a12

References

PMID: 9409754 by Mori K., et al. Kidney-specific expression of a novel mouse organic cation transporter-like protein.

PMID: 14747372 by Hosoyamada M., et al. Function and localization of urate transporter 1 in mouse kidney.