Sirpa Antibodies

AND Sirpa ELISA kits, Sirpa Proteins

Many biological assays use antibodies to detect Sirpa, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sirpa in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sirpa antibodies...

We validate the specificity of these antibodies to Sirpa by testing them on tissues known to express Sirpa positively and negatively. Browse below to find the Sirpa antibody that suites your experiment. We have 8 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Sirpa Infographic by Boster Bio

All Sirpa Products

Product

Figures

Specificity

Applications

Price

Sirp alpha1 Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$480
Cat # EKC1523
1 kit, containing one 96-well plate and all necessary reagents

Anti-SIRP alpha Antibody

Human, Mouse, Rat

ELISA, ICC, WB

$449
Cat # A05151
0.1 mg

Anti-SIRP-alpha Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A05151-1
100ul

Human SIRP alpha/CD172a Recombinant Protein

SDS-PAGE

$250
Cat # PROTP78324
Starting from 20ug

Rat SIRP alpha/CD172a Recombinant Protein

SDS-PAGE

$250
Cat # PROTP97710
Starting from 10ug

Anti-SIRP alpha (SIRPA) Mouse Monoclonal Antibody [Clone ID: OTI7B3]

Human

Flow Cytometry, IHC, WB

$523
Cat # M05151
100 µl

Anti-SIRP alpha Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # M05151-1
100 μl/vial

SIRP alpha (SIRPA) (NM_001040022) Human Over-expression Lysate

Human

$960
Cat # LS140885
100 µg

Sirpa Overview

Facts about Tyrosine-protein phosphatase non-receptor type substrate 1.

Tyrosine-protein phosphatase non-receptor type substrate 1 (Sirpa)

Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane.

Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play an integral role in intracellular signaling during synaptogenesis and in synaptic function.

Gene Information

Mouse
Gene Name:	Sirpa
Uniprot:	P97797
Entrez:	19261

Family

Belongs to:

No superfamily

Alternative Names

BIT; BITbrain-immunoglobulin-like molecule with tyrosine-based activation motifs; Brain Ig-like molecule with tyrosine-based activation motifs; CD172 antigen-like family member A; CD172a antigen; CD172a; Inhibitory receptor SHPS-1; Macrophage fusion receptor; MFR; MFRtyrosine phosphatase SHP substrate 1; MyD-1 antigen; MYD1; MYD-1; P84; protein tyrosine phosphatase, non-receptor type substrate 1; PTPNS1; SHP substrate 1; SHPS1; SHPS-1; SHPS1CD172A; signal-regulatory protein alpha; Signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP alph

Molecular Weight

Mass (kDA):
56.414 kDA

Genomic Context


Mouse

Location:	2 F1\|2 63.19 cM
Sequence:	2;

Tissue Specificity

Highly expressed in cerebral cortex, brain, spinal cord, cerebellum and spleen, and at much lower levels in kidney, thymus, heart, lung and liver. Within the cerebellum, highly expressed throughout the molecular layer, and in synaptic glomeruli in the granule cell layer. Detected in neurons of the hippocampus and dentate gyrus, and in olfactory bulb. Not detected in Purkinje cells. Highly expressed in the plexiform layers, optic fiber layer and the outer segments of the photoreceptor layer in the retina. Highly expressed in macrophages. Isoform 3 is detected at very low levels in all tissues tested.