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- Table of Contents
Facts about Secretion-regulating guanine nucleotide exchange factor.
Human | |
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Gene Name: | SERGEF |
Uniprot: | Q9UGK8 |
Entrez: | 26297 |
Belongs to: |
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No superfamily |
Deafness locus-associated putative guanine nucleotide exchange factor; DelGEF; DELGEFdeafness locus associated putative guanine nucleotide exchange factor; Gnefr; Guanine nucleotide exchange factor-related protein; secretion regulating guanine nucleotide exchange factor; secretion-regulating guanine nucleotide exchange factor
Mass (kDA):
48.981 kDA
Human | |
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Location: | 11p15.1 |
Sequence: | 11; NC_000011.10 (17788048..18013047, complement) |
Cytoplasm. Nucleus.
PMID: 10571079 by Uhlmann J., et al. DelGEF, an RCC1-related protein encoded by a gene on chromosome 11p14 critical for two forms of hereditary deafness.
PMID: 12459492 by Sjoelinder M., et al. DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates secretion.