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P-selectin Antibodies
AND SELP ELISA kits, P-selectin Proteins
Many biological assays use antibodies to detect P-selectin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with P-selectin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop P-selectin antibodies...
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SELP Infographic by Boster Bio
All SELP Products
Product
Figures
Specificity
Applications
Price
Anti-CD62P/SELP Antibody Picoband®
1 Citations 1 Q&As
Human
ELISA, Flow Cytometry, IHC, ICC, WB
$370
Cat # PB9363
100 μg/vial
Cat # PB9363
100 μg/vial
Human P-Selectin / CD62P ELISA Kit PicoKine®
5 Citations 6 Q&As
Human
ELISA
$499
Cat # EK0505
96 wells/kit, with removable strips.
Cat # EK0505
96 wells/kit, with removable strips.
Mouse P-Selectin / CD62P ELISA Kit PicoKine®
7 Citations 6 Q&As
Mouse
ELISA
$499
Cat # EK0506
96 wells/kit, with removable strips.
Cat # EK0506
96 wells/kit, with removable strips.
Anti-CD62P/Selp Antibody Picoband®
2 Citations 1 Q&As
Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A01241-1
100 μg/vial
Cat # A01241-1
100 μg/vial
Mouse
Flow Cytometry
$515
Cat # A01241-Dyl488
100 μg/vial
Cat # A01241-Dyl488
100 μg/vial
Mouse
Flow Cytometry
$515
Cat # A01241-Dyl550
100 μg/vial
Cat # A01241-Dyl550
100 μg/vial
Human
ELISA
$499
Cat # FEK0505
96 wells/kit, with removable strips.
Cat # FEK0505
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # FEK0506
96 wells/kit, with removable strips.
Cat # FEK0506
96 wells/kit, with removable strips.
Human, Primate
Flow Cytometry, IP, ICC, WB
$299
Cat # M01241-1
0.1 mg
Cat # M01241-1
0.1 mg
SELP Overview
Facts about P-selectin.
P-selectin (SELP)
Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes.
The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the first steps in inflammation through interaction with SELPLG.
Gene Information
| Human | |
|---|---|
| Gene Name: | SELP |
| Uniprot: | P16109 |
| Entrez: | 6403 |
Family
| Belongs to: |
|---|
| selectin/LECAM family |
Alternative Names
CD62P antigen; CD62P; FLJ45155; GMP140; GRMP; PADGEM; PADGEMantigen CD62); PSEL; P-Selectin; selectin P (granule membrane protein 140kDa, antigen CD62); SELP
Molecular Weight
Mass (kDA):
90.834 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q24.2 |
| Sequence: | 1; NC_000001.11 (169588849..169630125, complement) |
Tissue Specificity
Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Diseases
- Tissue Adhesions
- Inflammation
- Malignant Neoplasms
- Atherosclerosis
- Cardiovascular Diseases
- Neoplasms
- Heart Diseases
- Inflammatory Response
- Malignant Head And Neck Neoplasm
- Von Willebrand Disease
- Infarction
- Myocardial Infarction
- Head And Neck Neoplasms
Interacting Proteins
- SELPLG
Pathways
- Cell Adhesion
- Platelet Activation
- Pathogenesis
- Inflammatory Response
- Platelet Aggregation
- Aging
- Cell Activation
- Immune Response
- Endothelial Cell Activation
- Angiogenesis
- Transport
- Hypersensitivity
- Virulence
PTMs
- Phosphorylation
- Nitration
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SELP
bosterbio.com/bosterbio-gene-info-cards/SELP
References
PMID: 2466574 by Johnston G.I., et al. Cloning of GMP-140, a granule membrane protein of platelets and endothelium: sequence similarity to proteins involved in cell adhesion and inflammation.
PMID: 7684381 by Fujimoto T., et al. P-selectin is acylated with palmitic acid and stearic acid at cysteine 766 through a thioester linkage.
13 Publications of Boster P-selectin Antibodies & ELISA Kits
- PubMed ID: 10.3892/mmr.2016.5294, Effects of the eukaryotic initiation factor 6 gene on expression levels of infla...
- PubMed ID: 10.1016/j.colsurfb.2012.02.018, Fabrication of biomolecule-PEG micropattern on titanium surface and its effects ...
- PubMed ID: 10.1007/s10753-014-9918-x, Simvastatin Inhibits Inflammation in Ischemia-Reperfusion Injury
- PubMed ID: -, Nesibe,E.Y.,& KONUKOĞLU,D.(2021).Plasma Levels of Soluble P-Selectin, Beta-Thro...
- PubMed ID: 33046059, Guo J,Li M,Yang Y,Zhang L,Zhang LW,Sun QY.Pretreatment with atorvastatin amelior...
- PubMed ID: 32934963, Zhang R,Ji J,Zhou X,Li R.Irisin Pretreatment Protects Kidneys against Acute Kidn...
- PubMed ID: 33253922, Shu G,Lu C,Wang Z,Du Y,Xu X,Xu M,Zhao Z,Chen M,Dai Y,Weng Q,Fang S,Fan K,Liu D,D...
- PubMed ID: 24734087, Plasma Vitamin D Status and Its Correlation with Risk Factors of Thrombosis, P-s...
- PubMed ID: 28633041, Fayed, M.A., Abdel-Hady, H.E., Hafez, M.M., Salama, O.S., & Al-Tonbary, Y.A. (20...
- PubMed ID: 24992835, Tun X, Yasukawa K, Yamada K. Free Radic Biol Med. 2014 Sep;74:108-17. Doi: 10.10...
- PubMed ID: 22998024, Yasukawa K, Tokuda H, Tun X, Utsumi H, Yamada K. Free Radic Res. 2012 Dec;46(12)...
- PubMed ID: 26038476, Li L, Ben Y, Yuan S, Liu A, Wu H, Xu J, Zhang X. Emerg Microbes Infect. 2013 Jul...
- PubMed ID: 22391529, Zhong M, He B, Yang J, Bao R, Zhang Y, Zhou D, Chen Y, Li L, Han C, Yang Y, Sun ...
*More publications can be found for each product on its corresponding product page