Synaptopodin Antibodies

AND SYNPO ELISA kits, Synaptopodin Proteins

Many biological assays use antibodies to detect Synaptopodin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Synaptopodin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Synaptopodin antibodies...

We validate the specificity of these antibodies to Synaptopodin by testing them on tissues known to express SYNPO positively and negatively. Browse below to find the SYNPO antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SYNPO Infographic by Boster Bio

All SYNPO Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Synaptopodin/SYNPO Antibody Picoband®

4 Q&As

Human, Mouse

$370
Cat # RP1069
100 μg/vial

Anti-Synaptopodin SYNPO Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A03154
0.1 mg

Anti-Synaptopodin/SYNPO Antibody Picoband®

1 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A03154-1
100 μg/vial

SYNPO Overview

Facts about Synaptopodin.

SYNPO 3D structure. Source: alphafold

Synaptopodin (SYNPO)

Actin-associated protein which may play a role in regulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Appears to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity (By similarity).

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Gene Information

Human
Gene Name:	SYNPO
Uniprot:	Q8N3V7
Entrez:	11346

Family

Belongs to:

synaptopodin family

Alternative Names

KIAA1029; Synaptopodin; SYNPO

Molecular Weight

Mass (kDA):
99.463 kDA

Genomic Context


Human

Location:	5q33.1
Sequence:	5; NC_000005.10 (150586026..150659214)

Tissue Specificity

Expressed in cerebral cortex.

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell junction, tight junction. Perikaryon. Cell projection, dendritic spine. Cell junction, synapse, postsynaptic density. Cell junction, synapse. Cytoplasm, cytosol. Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Associated with dendritic spines of a subset of synapses.

Diseases

Kidney Diseases
Proteinuria Of Undiagnosed Cause
Glomerulosclerosis (disorder)
Focal Glomerulosclerosis
Neoplasms
Segmental Glomerulosclerosis
Diabetic Nephropathy
Aids-associated Nephropathy
Sclerosis
Nephrotic Syndrome
Renal Glomerular Disease
Nephroblastoma
Glomerulonephritis

Anaplasia
Diabetes Mellitus
Glomerulonephritis, Minimal Change
Kidney Failure, Chronic
Kidney Failure
Macular Corneal Dystrophy Type I
Hyperplasia

Interacting Proteins

ACTN1

Pathways

Pathogenesis
Localization
Glomerular Filtration
Dedifferentiation
Excretion
Gene Silencing
Cell Migration
Cell Cycle
Cell Proliferation
Transport
Cell Division
Membrane Depolarization
Cell Motility

Regulation Of Synaptic Plasticity
Cell Adhesion
Neurogenesis
Tropism
Nuclear Export
Cell Cycle Arrest
Inflammatory Response

PTMs

Phosphorylation
Cleavage

Ubiquitination
Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SYNPO

References

PMID: 9314539 by Mundel P., et al. Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes.

PMID: 12042308 by Patrie K.M., et al. Interaction of two actin-binding proteins, synaptopodin and alpha- actinin-4, with the tight junction protein MAGI-1.