Sulfotransferase family cytosolic 1B member 1 (SULT1B1)

Sulfotransferase that uses 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also lead to bioactivation to form active metabolites.

Sulfates dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, such as 3,3'-diiodothyronine, triidothyronine, reverse triiodothyronine and thyroxine. .