Sufu Antibodies

AND Sufu ELISA kits, Sufu Proteins

Many biological assays use antibodies to detect Sufu, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sufu in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sufu antibodies...

We validate the specificity of these antibodies to Sufu by testing them on tissues known to express Sufu positively and negatively. Browse below to find the Sufu antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Sufu Infographic by Boster Bio

All Sufu Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SUFU Picoband® Antibody

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A02279-1
100 μg/vial

Anti-Suppressor of fused homolog SUFU Antibody

Human, Mouse, Rat

IF, IHC-P, ICC, WB

$405
Cat # A02279-2
100ul

Human SUFU Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9UMX1
Starting from 20ug

Suppressor of Fused (SUFU) (NM_016169) Human Over-expression Lysate

Human

$628
Cat # LS051684
100 µg

Sufu Overview

Facts about Suppressor of fused homolog.

Suppressor of fused homolog (Sufu)

Negative regulator in the hedgehog/smoothened signaling pathway (PubMed:16155214, PubMed:16459298). Down-regulates GLI1- mediated transactivation of target genes.

Section of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 into BTRC and thereby targeting GLI1 to degradation by the proteasome.

Gene Information

Mouse
Gene Name:	Sufu
Uniprot:	Q9Z0P7
Entrez:	24069

Family

Belongs to:

SUFU family

Alternative Names

SUFUHSUFUXLPRO1280; suppressor of fused homolog (Drosophila); suppressor of fused homolog

Molecular Weight

Mass (kDA):
53.957 kDA

Genomic Context


Mouse

Location:	19 C3\|19 38.85 cM
Sequence:	19;

Tissue Specificity

Widely expressed in adult and fetal tissues.

Diseases

Malignant Neoplasms
Neoplasms
Medulloblastoma
Carcinoma
Basal Cell Carcinoma
Cell Transformation, Neoplastic
Cerebellar Neoplasms
Carcinogenesis
Brain Neoplasms
Basal Cell Nevus Syndrome
Malignant Neoplasm Of Stomach
Desmoplastic
Malignant Paraganglionic Neoplasm

Leukemia
Adenocarcinoma
Malignant Neoplasm Of Prostate
Rhabdomyosarcoma
Esophageal Neoplasms
Malignant Neoplasm Of Pancreas
Skin Neoplasms

Pathways

Localization
Fermentation
Pathogenesis
Cell Proliferation
Tissue Homeostasis
Aging
Nuclear Export
Cell Growth
Cell Differentiation
Cell Cycle
Nuclear Import
Sex Determination
Limb Development

Spermatogenesis
Intraflagellar Transport
Spinal Cord Patterning
Transport
Proteolysis
Cell Fate Determination
Neurogenesis

PTMs

Phosphorylation
Cleavage
Methylation

Ubiquitination
Reduction
Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Sufu

References

PMID: 10531011 by Ding Q., et al. Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1.

PMID: 11252182 by Delattre M., et al. Suppressor of fused gene involved in hedgehog signal transduction in Drosophila melanogaster is conserved in mammals.