SUCLG1 Antibodies

AND SUCLG1 ELISA kits, SUCLG1 Proteins

Many biological assays use antibodies to detect SUCLG1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SUCLG1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SUCLG1 antibodies...

We validate the specificity of these antibodies to SUCLG1 by testing them on tissues known to express SUCLG1 positively and negatively. Browse below to find the SUCLG1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SUCLG1 Infographic by Boster Bio

All SUCLG1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SUCLG1 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A06274
100ul

SUCLG1 (NM_003849) Human Over-expression Lysate

Human

$628
Cat # LS008802
100 µg

Anti-SUCLG1 Antibody Picoband®

Human, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A06274-1
100 µg/vial

SUCLG1 Overview

Facts about Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial.

SUCLG1 3D structure. Source: alphafold

Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (SUCLG1)

Succinyl-CoA synthetase functions from the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP or GTP and so represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of this enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for ATP or GTP is supplied by different beta subunits.

Gene Information

Human
Gene Name:	SUCLG1
Uniprot:	P53597
Entrez:	8802

Family

Belongs to:

succinate/malate CoA ligase alpha subunit family

Alternative Names

EC 6.2.1; EC 6.2.1.4; FLJ21114; FLJ43513; GALPHA; MTDPS9; SCS-alpha; succinate-CoA ligase, alpha subunit; succinate-CoA ligase, GDP-forming, alpha subunit; succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase subunit alpha; SUCLA1

Molecular Weight

Mass (kDA):
36.25 kDA

Genomic Context


Human

Location:	2p11.2
Sequence:	2; NC_000002.12 (84423528..84459280, complement)

Subcellular Localizations

Mitochondrion.

Diseases

Mitochondrial Dna Depletion
Mitochondrial Diseases
Acidosis
Acidosis, Lactic
Methylmalonic Acidemia
Mitochondrial Encephalomyopathies
Mitochondrial Respiratory Chain Deficiencies
Muscle Hypotonia
Dysmyelopoietic Syndromes
Leigh Disease
Fetal Growth Retardation

Liver Diseases
Weakness
Genetic Diseases, Inborn
Mastitis-metritis-agalactia Syndrome
Myopathy

Pathways

Translation
Oxidative Phosphorylation
Pathogenesis
Excretion

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SUCLG1

References

PMID: 9128182 by James M., et al. The molecular basis for cross-reaction anti-dystrophin antibody with alpha-actinin.

PMID: 17668387 by Ostergaard E., et al. Deficiency of the alpha subunit of succinate-coenzyme A ligase causes fatal infantile lactic acidosis with mitochondrial DNA depletion.