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- Table of Contents
Facts about Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5.
Involved in the biosynthesis of ganglioside GD1a from GM1b.
It exhibits higher activity with glycolipids than with glycoproteins..
Mouse | |
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Gene Name: | St6galnac5 |
Uniprot: | Q9QYJ1 |
Entrez: | 26938 |
Belongs to: |
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glycosyltransferase 29 family |
alpha-N-acetylneuraminyl 2,3-betagalactosyl-1,3)-N-acetyl galactosaminidealpha-2,6-sialyltransferase E; EC 2.4.99; EC 2.4.99.-; EC 2.4.99.7; GalNAc alpha-2,6-sialyltransferase V; GD1 alpha synthase; MGC3184; sialyltransferase 7 (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase) E; sialyltransferase 7((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminidealpha-2,6-sialyltransferase) E; Sialyltransferase 7E; SIAT7E; SIAT7-E; SIAT7Ealpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase V; ST6 (alpha-N-acetyl-neuraminyl-2
Mass (kDA):
38.43 kDA
Mouse | |
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Location: | 3|3 H3 |
Sequence: | 3; |
High expression in forebrain and to a lesser extent in cerebellum. No expression in salivary gland, intestine, liver, kidney, heart, lung, thymus and spleen.
PMID: 10601645 by Ikehara Y., et al. A novel glycosyltransferase with a polyglutamine repeat; a new candidate for GD1alpha synthase (ST6GalNAc V).
PMID: 10521438 by Okajima T., et al. Molecular cloning of brain specific GD1alpha synthase (ST6GalNAc V) containing CAG/glutamine repeats.