Sorcin Antibodies

AND SRI ELISA kits, Sorcin Proteins

Many biological assays use antibodies to detect Sorcin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sorcin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sorcin antibodies...

We validate the specificity of these antibodies to Sorcin by testing them on tissues known to express SRI positively and negatively. Browse below to find the SRI antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SRI Infographic by Boster Bio

All SRI Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SR1/SRI Antibody Picoband®

1 Q&As

Human, Rat

$370
Cat # RP1110
100 μg/vial

Anti-SRI Antibody Picoband®

4 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, IHC, IHC-F, ICC, WB

$370
Cat # A00222
100 μg/vial

Anti-Sorcin SRI Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A00222-1
100ul

SR1 (SRI) (NM_003130) Human Recombinant Protein

$813
Cat # PROTP30626
20 µg

Anti-SRI Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A00222-2
100 μg/vial

SR1 (SRI) (NM_003130) Human Over-expression Lysate

Human

$628
Cat # LS006717
100 µg

SRI Overview

Facts about Sorcin.

SRI 3D structure. Source: alphafold

Sorcin (SRI)

Calcium-binding protein that modulates excitation- contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum.

Modulates the activity of RYR2 calcium channels. .

Gene Information

Human
Gene Name:	SRI
Uniprot:	P30626
Entrez:	6717

Family

Belongs to:

No superfamily

Alternative Names

calcium binding protein amplified in mutlidrug-resistant cells; CP22; CP-22; FLJ26259,22 kDa protein; H_RG167B05.1; SCN; sorcin; V19

Molecular Weight

Mass (kDA):
21.676 kDA

Genomic Context


Human

Location:	7q21.12
Sequence:	7; NC_000007.14 (88205115..88226993, complement)

Tissue Specificity

Detected in cardiac myocytes.

Subcellular Localizations

Cytoplasm. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels.

Diseases

Obsessive-compulsive Disorder
Osteochondritis Dissecans
Depressive Disorder
Corneal Diseases
Anxiety Disorders
Neoplasms
Malignant Neoplasms
Major Depressive Disorder
Mental Disorders
Infarction
Myocardial Infarction
Hypertensive Disease

Ventricular Dysfunction, Left
Ischemia
Coronary Artery Disease
Myocardial Ischemia
Hypotension Adverse Event
Obsessive Compulsive Behavior

Interacting Proteins

ANXA7
CALCOCO2
PRR13
STAT3
TCF12

Pathways

Phototaxis
Transport
Platelet Aggregation
Pathogenesis
Localization
Drug Resistance
Negative Phototaxis
Chemotaxis
Vasoconstriction
Proton Transport
Methylation
Secretion
Positive Phototaxis

Vasodilation
Cell Growth
Translation
Platelet Activation
Aging
Ion Transport
Swimming

PTMs

Phosphorylation
Methylation
Cleavage
Demethylation

Nitration
Reduction
Carboxylation
Dephosphorylation

Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SRI

References

PMID: 7873602 by Wang S.L., et al. Isolation and molecular cloning of human sorcin a calcium-binding protein in vincristine-resistant HOB1 lymphoma cells.

PMID: 8561500 by Lee W.P.; Purification, cDNA cloning, and expression of human sorcin in vincristine-resistant HOB1 lymphoma cell lines.