Osteopontin Antibodies

AND SPP1 ELISA kits, Osteopontin Proteins

Many biological assays use antibodies to detect Osteopontin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Osteopontin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Osteopontin antibodies...

We validate the specificity of these antibodies to Osteopontin by testing them on tissues known to express SPP1 positively and negatively. Browse below to find the SPP1 antibody that suites your experiment. We have 11 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SPP1 Infographic by Boster Bio

All SPP1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Osteopontin/SPP1 Antibody Picoband®

10 Citations 5 Q&As

Human, Mouse, Rat

ELISA, WB

$370
Cat # RP1080
100 μg/vial

Human OPN / Osteopontin ELISA Kit PicoKine®

15 Citations 8 Q&As

Human

ELISA

$499
Cat # EK0482
96 wells/kit, with removable strips.

Mouse OPN / Osteopontin ELISA Kit PicoKine®

6 Citations 5 Q&As

Mouse

ELISA

$499
Cat # EK0483
96 wells/kit, with removable strips.

Anti-Osteopontin/SPP1 Antibody Picoband®

5 Citations 17 Q&As

Human

$370
Cat # PA1431
100 μg/vial

Anti-Osteopontin SPP1 Rabbit Monoclonal Antibody

2 Citations 16 Q&As

Human, Mouse

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M00634
100 μl

SPP1 Human, Osteopontin Human Recombinant Protein, HEK

1 Citations

Human

$250
Cat # PROTP10451
10ug, 50ug, 1mg

Anti-Osteopontin SPP1 Antibody

11 Citations 15 Q&As

Human

ELISA, IHC, WB

$629
Cat # A00634
200uL

Osteopontin Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$480
Cat # EKC1415
1 kit, containing one 96-well plate and all necessary reagents

Anti-Yeast SPP1 Antibody

Yeast

$470
Cat # DZ00634
500 μl/vial

Anti-Osteopontin (SPP1) Mouse Monoclonal Antibody [Clone ID: OTI5E4]

Human

IHC, WB

$523
Cat # M00634-1
100 µl

Osteopontin (SPP1) (NM_001040058) Human Over-expression Lysate

Human

$628
Cat # LS006696
100 µg

SPP1 Overview

Facts about Osteopontin.

SPP1 3D structure. Source: alphafold

Osteopontin (SPP1)

Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix.

Probably important to cell-matrix interaction. .

Gene Information

Human
Gene Name:	SPP1
Uniprot:	P10451
Entrez:	6696

Family

Belongs to:

osteopontin family

Alternative Names

BNSP; Bone sialoprotein 1; Eta-1; MGC110940; Nephropontin; OPN; Osteopontin; secreted phosphoprotein 1bone sialoprotein I, early T-lymphocyteactivation 1); secreted phosphoprotein-1 (osteopontin, bone sialoprotein); Spp1; SPP-1; SPP1/CALPHA1 fusion; Urinary stone protein; uropontin

Molecular Weight

Mass (kDA):
35.423 kDA

Genomic Context


Human

Location:	4q22.1
Sequence:	4; NC_000004.12 (87975650..87983411)

Tissue Specificity

Bone. Found in plasma.

Subcellular Localizations

Secreted.

Diseases

Neoplasms
Tissue Adhesions
Malignant Neoplasms
Neoplasm Metastasis
Inflammation
Carcinoma
Fibrosis
Calcinosis
Cell Invasion
Kidney Diseases
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Breast

Hypertrophy
Osteosarcoma
Tumor Angiogenesis
Mammary Neoplasms
Atherosclerosis
Hyperplasia
Tumor Progression

Interacting Proteins

CD44
FAM20C
MEOX2
SGTA

Pathways

Cell Adhesion
Cell Proliferation
Localization
Pathogenesis
Secretion
Osteoblast Differentiation
Bone Resorption
Cell Migration
Regeneration
Angiogenesis
Cell Growth
Bone Remodeling
Cell Differentiation

Wound Healing
Ossification
Cell Death
Inflammatory Response
Chemotaxis
Excretion
Immune Response

PTMs

Phosphorylation
Cleavage
Glycosylation
Methylation
Dephosphorylation
Acetylation
Sulphation
Nitrosylation

Hydroxylation
Ubiquitination
Iodination
Nitration
Biotinylation
Citrullination
Ribosylation
Amination

Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPP1

References

PMID: 2726470 by Kiefer M.C., et al. The cDNA and derived amino acid sequence for human osteopontin.

PMID: 1974876 by Young M.F., et al. cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN).

38 Publications of Boster Osteopontin Antibodies & ELISA Kits

PubMed ID: 10.3892/etm.2015.2585, Renoprotective effects of berberine as adjuvant therapy for hypertensive patient...
PubMed ID: 10.14744/AnatolJCardiol.2019.88555, The association between serum angiogenin and osteopontin levels and coronary col...
PubMed ID: 10.1186/s13075-018-1547-6, Traditional Chinese medicine formula Bi-Qi capsule alleviates rheumatoid arthrit...
PubMed ID: 10.1159/000334058, Predictive Value of Serum Bone Sialoprotein in Patients with Bone Metastasis of ...
PubMed ID: 10.1111/febs.14754, Diminished membrane recruitment of Akt is instrumental in alcohol‐associated o...
PubMed ID: 10.1111/aor.13622, Avβ3 single‐stranded DNA aptamer attenuates vascular restenosis via Ras‐PI3...
PubMed ID: 10.1080/17435390.2018.1513093, Activated iRhom2 drives prolonged PM2.5 exposure-triggered renal injury in Nrf2-...
PubMed ID: 10.1021/acsami.9b14800, Surface Epitaxial Crystallization-Directed Nanotopography for Accelerating Preos...
PubMed ID: 10.1016/S1995-7645(13)60042-5, Expression of NF-κB and osteopontin of synovial fluid of patients with knee ost...
PubMed ID: 10.1016/j.yjmcc.2021.03.013, The role of ATG-7 contributes to pulmonary hypertension by impacting vascular re...
PubMed ID: 10.1016/j.polymer.2020.122462, Combination of nanolamellae and PDA coating on promoting the long-term adhesion,...
PubMed ID: 10.1016/j.msec.2018.11.006, Promoting osteoblast proliferation on polymer bone substitutes with bone-like st...
PubMed ID: 10.1016/j.biomaterials.2021.121260, An improved osseointegration of metal implants by pitavastatin loaded multilayer...
PubMed ID: 10.1016/j.apsusc.2019.03.193, Nanotopographical polymeric surface with mussel-inspired decoration to enhance o...
PubMed ID: 10.1002/jcp.28968, XIST/miR‐376c‐5p/OPN axis modulates the influence of proinflammatory M1 macr...
PubMed ID: 10.1002/jbm.a.36273, Functionalizing titanium surface with PAMAM dendrimer and human BMP2 gene via la...
PubMed ID: 10.1002/1878-0261.12399, Hypoxia‐driven paracrine osteopontin/integrin αvβ3 signaling promotes pancre...
PubMed ID: 10.1002/1878-0261.12399, Hypoxia‐driven paracrine osteopontin/integrin αvβ3 signaling promotes pancre...
PubMed ID: 33650080, Li X,Hu B,Wang L,Xia Q,Ni X. P2X7 receptor-mediated phenotype switching of pulmo...
PubMed ID: -, Caiyun Mu,Ye He,Yan Hu,Menghuan Li,Maowen Chen,Rong Wang,Yang Xiang, Zhong Luo,K...
PubMed ID: -, Chaowei Hu,Kun Zuo,Kuibao Li,Yuanfeng Gao,Mulei Chen,Roumu Hu,Ye Liu,Hongjie Chi...

*Showing only the more recent 20. More publications can be found for each product on its corresponding product page