Spondin-1 Antibodies

AND SPON1 ELISA kits, Spondin-1 Proteins

Many biological assays use antibodies to detect Spondin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Spondin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Spondin-1 antibodies...

We validate the specificity of these antibodies to Spondin-1 by testing them on tissues known to express SPON1 positively and negatively. Browse below to find the SPON1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SPON1 Infographic by Boster Bio

All SPON1 Products

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Product

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Specificity

Applications

Price

Anti-Spondin-1 SPON1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A03094
100ul

SPON1 (NM_006108) Human Over-expression Lysate

Human

$960
Cat # LS010418
100 µg

SPON1 Overview

Facts about Spondin-1.

SPON1 3D structure. Source: alphafold

Spondin-1 (SPON1)

Cell adhesion protein that promotes the attachment of both spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity).

Major factor for vascular smooth muscle cell. .

Gene Information

Human
Gene Name:	SPON1
Uniprot:	Q9HCB6
Entrez:	10418

Family

Belongs to:

No superfamily

Alternative Names

FSpondin; F-Spondin; KIAA0762VSGP/F-spondin; MGC10724; SPON1; spondin 1, (f-spondin) extracellular matrix protein; spondin 1, extracellular matrix protein; spondin-1; Vascular smooth muscle cell growth-promoting factor; VSGP

Molecular Weight

Mass (kDA):
90.973 kDA

Genomic Context


Human

Location:	11p15.2
Sequence:	11; NC_000011.10 (13962723..14268133)

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Carcinoma
Malignant Neoplasms
Nervousness
Ovarian Neoplasm
Tissue Adhesions
Tumor Angiogenesis
Neoplasms
Hypertensive Disease
Alzheimer's Disease
Malignant Neoplasm Of Ovary
Epithelial Ovarian Cancer
Pathologic Neovascularization
Corneal Diseases

Neoplasm Metastasis
Peritoneal Neoplasms
Periodontitis
Overlying Behavior
Malignant Neoplasm Of Breast
Muscular Dystrophy, Duchenne
Alveolar Bone Loss

Pathways

Pathogenesis
Cell Migration
Angiogenesis
Cell Proliferation
Glycosylation
Localization
Secretion
Cell Adhesion
Muscle Cell Proliferation
Mediolateral Intercalation
Tube Formation
Neurogenesis
Protein Glycosylation

Cell Motility
Axon Guidance
Smooth Muscle Cell Proliferation
Convergent Extension
Dna Methylation
Methylation
Regeneration

PTMs

Cleavage
Phosphorylation

Glycosylation
C-mannosylation

Research Areas

Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPON1

References

PMID: 11368520 by Miyamoto K., et al. Isolation and characterization of vascular smooth muscle cell growth promoting factor from bovine ovarian follicular fluid and its cDNA cloning from bovine and human ovary.

PMID: 12096136 by Gonzalez de Peredo A., et al. C-mannosylation and O-fucosylation of thrombospondin type 1 repeats.