SPINK1 Antibodies

AND SPINK1 ELISA kits, SPINK1 Proteins

Many biological assays use antibodies to detect SPINK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SPINK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SPINK1 antibodies...

We validate the specificity of these antibodies to SPINK1 by testing them on tissues known to express SPINK1 positively and negatively. Browse below to find the SPINK1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SPINK1 Infographic by Boster Bio

All SPINK1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human SPINK1/TATI ELISA Kit PicoKine®

3 Citations 7 Q&As

Human

ELISA

$750
Cat # EK1241
96 wells/kit, with removable strips.

Human SPINK1 Recombinant Protein

SDS-PAGE

$265
Cat # PROTP00995
Starting from 20ug

Anti-SPINK1 Rabbit Monoclonal Antibody

Human

IHC, WB

$370
Cat # M00982
100 μl/vial

SPINK1 (NM_003122) Human Over-expression Lysate

Human

$628
Cat # LS006690
100 µg

SPINK1 Overview

Facts about Serine protease inhibitor Kazal-type 1.

SPINK1 3D structure. Source: alphafold

Serine protease inhibitor Kazal-type 1 (SPINK1)

Serine protease inhibitor which shows anti-trypsin activity (PubMed:7142173). In the pancreas, protects against trypsin-catalyzed premature activation of zymogens (By similarity).

Gene Information

Human
Gene Name:	SPINK1
Uniprot:	P00995
Entrez:	6690

Family

Belongs to:

No superfamily

Alternative Names

pancreatic secretory trypsin inhibitor; PCTT; PCTTSpink3; PSTI; PSTISerine protease inhibitor Kazal-type 1; serine peptidase inhibitor, Kazal type 1; serine protease inhibitor, Kazal type 1; SPINK1; Spink3; TATI; TATITumor-associated trypsin inhibitor

Molecular Weight

Mass (kDA):
8.507 kDA

Genomic Context


Human

Location:	5q32
Sequence:	5; NC_000005.10 (147824580..147839231, complement)

Subcellular Localizations

Secreted.

Diseases

Pancreatitis
Pancreatitis, Chronic
Fibrosis
Malignant Neoplasms
Cystic Fibrosis
Acute Pancreatitis
Malignant Neoplasm Of Pancreas
Diabetes Mellitus
Pancreatitis, Alcoholic
Pancreatic Neoplasm
Pain

Acute Recurrent Pancreatitis
Neoplasms
Pancreatic Diseases
Malignant Neoplasm Of Prostate
Inflammation

Pathways

Secretion
Pathogenesis
Trypsinogen Activation
Autophagy
Inflammatory Response
Cell Proliferation
Localization
Cell Death
Transport
Protein Secretion
Hormone Secretion
Regeneration
Autophagic Cell Death

Cell Growth
Protein Phosphorylation
Cell Adhesion
Cell Migration
Proteolysis
Immune Response
Reflex

PTMs

Phosphorylation
Methylation

Cleavage
Glycosylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPINK1

References

PMID: 3501289 by Horii A., et al. Primary structure of human pancreatic secretory trypsin inhibitor (PSTI) gene.

PMID: 3877508 by Yamamoto T., et al. Molecular cloning and nucleotide sequence of human pancreatic secretory trypsin inhibitor (PSTI) cDNA.

3 Publications of Boster SPINK1 Antibodies & ELISA Kits

PubMed ID: 10.18632/oncotarget.5927, Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis...
PubMed ID: 10.1038/s41388-020-01451-4, Targeting an autocrine IL-6–SPINK1 signaling axis to suppress metastatic sprea...
PubMed ID: 26437224, Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis...

*More publications can be found for each product on its corresponding product page