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- Table of Contents
Facts about Transcription factor SOX-3.
Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also inside the pharyngeal epithelia for craniofacial morphogenesis.
Human | |
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Gene Name: | SOX3 |
Uniprot: | P41225 |
Entrez: | 6658 |
Belongs to: |
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No superfamily |
GHDX; MRGH; panhypopituitarism; PHP; PHPX; SOX3; SOXB; SRY (sex determining region Y)-box 3; transcription factor SOX-3
Mass (kDA):
45.21 kDA
Human | |
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Location: | Xq27.1 |
Sequence: | X; NC_000023.11 (140502985..140505069, complement) |
Nucleus.
PMID: 8111369 by Stevanovic M., et al. SOX3 is an X-linked gene related to SRY.
PMID: 1614875 by Denny P., et al. A conserved family of genes related to the testis determining gene, SRY.