This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
, No Gclids
SOX2 Antibodies
AND SOX2 ELISA kits, SOX2 Proteins
Many biological assays use antibodies to detect SOX2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SOX2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SOX2 antibodies...
Previous: CBLIF
Next: SOX12
SOX2 Infographic by Boster Bio
All SOX2 Products
Product
Figures
Specificity
Applications
Price
Anti-Transcription factor SOX-2 SOX2 Antibody Picoband®
2 Citations 17 Q&As
Human, Mouse, Rat
IHC, WB
$370
Cat # PA2284
100 μg/vial
Cat # PA2284
100 μg/vial
Human, Mouse
ELISA, IHC, WB
$486
Cat # M00105
100ug/vial
Cat # M00105
100ug/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M00105-1
100 μl
Cat # M00105-1
100 μl
Human, Mouse, Rat
ELISA, IF, IHC-P, ICC, WB
$449
Cat # A00105
0.1 mg
Cat # A00105
0.1 mg
SOX2 Overview
Facts about Transcription factor SOX-2.
Transcription factor SOX-2 (SOX2)
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development like YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency.
May function as a change in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | SOX2 |
| Uniprot: | P48431 |
| Entrez: | 6657 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
ANOP3; MCOPS3; MGC2413; SOX2; SRY (sex determining region Y)-box 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2
Molecular Weight
Mass (kDA):
34.31 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3q26.33 |
| Sequence: | 3; NC_000003.12 (181711925..181714436) |
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Malignant Neoplasms
- Idiopathic Pneumonia Syndrome
- Teratoma
- Carcinoma
- Nervousness
- Cell Transformation, Neoplastic
- Malignant Paraganglionic Neoplasm
- Leukemia
- Embryonal Carcinoma
- Immunologic Deficiency Syndromes
- Brain Neoplasms
Interacting Proteins
- MBD3
- POU5F1
- PRKCI
- SUMO1
- VRK1
Pathways
- Cell Differentiation
- Neurogenesis
- Cell Proliferation
- Methylation
- Cell Cycle
- Regeneration
- Dna Methylation
- Pathogenesis
- Localization
- Chromatin Remodeling
- Cell Growth
- Cell Death
- Rna Interference
PTMs
- Methylation
- Phosphorylation
- Acetylation
- Demethylation
- Cleavage
- Sumoylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SOX2
bosterbio.com/bosterbio-gene-info-cards/SOX2
References
PMID: 7849401 by Stevanovic M., et al. The cDNA sequence and chromosomal location of the human SOX2 gene.
PMID: 12612584 by Fantes J., et al. Mutations in SOX2 cause anophthalmia.
2 Publications of Boster SOX2 Antibodies & ELISA Kits
- PubMed ID: 29531534, Yi H, Xie B, Liu B, Wang X, Xu L, Liu J, Li M, Zhong X, Peng F. Stem Cells Int. ...
- PubMed ID: 25888093, Cheng Z, Wang Hz, Li X, Wu Z, Han Y, Li Y, Chen G, Xie X, Huang Y, Du Z, Zhou Y....
*More publications can be found for each product on its corresponding product page