Protein SOX-15 Antibodies

Protein SOX-15 (SOX15)

Binds to the 5'-AACAAT-3' sequence. .

Gene Information

Human
Gene Name:	SOX15
Uniprot:	O60248
Entrez:	6665

Family

Belongs to:
No superfamily

Alternative Names

protein SOX-15; SOX15; SOX20; SOX20Protein SOX-20; SOX26; SOX26SOX12; SOX27; SOX27Protein SOX-12; SRY (sex determining region Y)-box 15; SRY (sex determining region Y)-box 20

Molecular Weight

Mass (kDA):
25.251 kDA

Genomic Context

Human
Location:	17p13.1
Sequence:	17; NC_000017.11 (7588178..7590094, complement)

Subcellular Localizations

Nucleus.

Diseases

• Carcinoma
• Testicular Neoplasms
• Embryonal Carcinoma
• Malignant Tumor Of Colon
• Malignant Paraganglionic Neoplasm
• Endometrial Polyp
• Crushing Injury
• Idiopathic Pneumonia Syndrome
• Choriocarcinoma

• Fetal Death
• Endometriosis, Site Unspecified
• Malignant Neoplasms
• Nervousness

Interacting Proteins

• BHLHE40
• HSFY1

Pathways

• Regeneration
• Cell Differentiation
• Cell Cycle
• Sex Determination
• Trophoblast Giant Cell Differentiation
• Socket Cell Differentiation
• Cell Proliferation
• Gastrulation
• Pancreas Development
• Developmental Process
• Regulation Of Growth
• Dna Methylation

• Oocyte Maturation
• Methylation
• Tissue Regeneration
• Sex Differentiation
• Regulation Of Cell Proliferation
• Pathogenesis
• Meiosis

PTMs

• Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SOX15

Boster Bio - Best Uses Of The SOX15 Marker

This article will give you an introduction to Steven Boster, SOX15 marks, High-affinity secondary antibodies, and SOXS package. The SOX trilogy genes are involved in cell signaling and the activation of many SOX protein. We need to understand how to study these proteins in order to understand their role in our health and disease. This article will present the most widely used methods of SOX gene elicitation and discuss the best uses each antibody for SOX genes.

Primary antibodies with high affinity

We created high-affinity primary antibody against SOX15 by immobilizing synthetic peptides outside of the HMG domain. The peptide could be conjugated to keyhole hemocyanin with a Sulfolink kits. The manufacturer's instructions for affinity purification were followed. Finally, we visualized the antigen in cryosections.

The SOX15 gene expression pattern was linked with lung cancer progression. High levels of nuclear b-catenin, Twist1, E-cadherin, Sox15, and CD133 were associated with a high-grade tumor. These markers could predict poor patient outcomes in lung carcinoma. High-affinity primary antibodies that target SOX15 could be helpful in detecting and tracking the cancer cells in a tumor sample.

SOXS Package

The SOX15 marker is a transcription factor that promotes the development of chondrogenic cells from mesenchymal stem cells. Boster Bio sells kits and antibodies to target the three genes. These antibodies are highly cited and validated on Western Blotting, Immunohistochemistry, and ELISA. Boster Bio antibodies have been used for more than 100 research studies. They are highly sensitive, specific, and well-respected.

SOX trio genes

The SOX15 protein is found in both human and mice mesenchymal strom cells (MSCs). This gene is essential for the differentiation of these cells into chondrocytes, which are vital for the development of cartilage. MSCs do not contain the SOX15 genes, but they can be transfected with the transforming growth hormone-I21.